Tashenatlas der Pharmakologie

ISBN-10: 3137817048

ISBN-13: 9783137817048

Edition: 4th 2011

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Fourth Edition of the classic pocket guide to pharmacology -- with access to WinkingSkull.com PLUSReflecting the most recent advances in the field, this up-to-date Fourth Edition is a succinct yet comprehensive source of information on basic pharmacologic structures and key pharmacotherapeutic connections. Each two-page spread contains concise text on the left complemented by detailed, full-color illustrations on the right to help users quickly digest important facts and concepts.Four color-coded sections provide readers with a solid framework with which to approach the latest developments in pharmacology:Part 1: General Pharmacology explains substance formulation, absorption, distribution, elimination, and molecular mechanisms of action.Part 2: Systems Pharmacology places special emphasis on the functional and therapeutic aspects of a wide range of medicinal agents.Part 3: Therapy of Selected Diseases presents expanded coverage of migraines, sleep disorders, and obesity.Part 4: Drug Index contains the most current data on over 700 drugs listed by their generic and brand names.FeaturesA user-friendly format ideal for studying, self-assessment, and quick referenceNew information on drug transporters, septic shock, substance P and amino acids, and more170 updated, full-color plates enhance the textNew in this edition -- a complete glossary of general pharmacology termsAdditional feature: A scratch-off code provides access to WinkingSkull.com PLUS, an interactive online study aid, featuring multiple choice pharmacology questions.The Fourth Edition of Color Atlas of Pharmacology is an essential study guide and reference for every busy student, nurse, and practicing physician who needs to keep on the cutting-edge.
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Book details

List price: $65.00
Edition: 4th
Copyright year: 2011
Publisher: Thieme Medical Publishers, Incorporated
Publication date: 11/24/2010
Binding: Paperback
Pages: 404
Size: 5.25" wide x 7.50" long x 1.00" tall
Weight: 1.100
Language: English

General Pharmacology
History of Pharmacology
The Idea
The Impetus
Early Beginnings
Consolidation-General Recognition
Status Quo
Drug Sources
Drug and Active Principle
The Aims of Isolating Active Principles
Plants as Sources of Effective Medicines
Drug Development
Congeneric Drugs and Name Diversity
Drug Administration
Oral Dosage Forms
Drug Administration by Inhalation
Dermatological Agents
Skin Protection
Dermatological Agents as Vehicles
From Administration to Distribution in the Body
Cellular Sites of Action
Potential Targets of Drug Action
Distribution in the Body
External Barriers of the Body
Blood-Tissue Barriers
Membrane Permeation
Drug Transporters
Possible Modes of Drug Distribution
Binding to Plasma Proteins
Drug Elimination
The Liver as an Excretory Organ
Biotransformation of Drugs
Drug Metabolism by Cytochrome P450
Enterohepatic Circulation
Conjugation Reactions
The Kidney as an Excretory Organ
Presystemic Elimination
Drug Concentration in the Body as a Function of Time-First Order (Exponential) Rate Processes
Time Course of Drug Concentration in Plasma
Time Course of Drug Plasma Levels during Repeated Dosing
Time Course of Drug Plasma Levels during Irregular Intake
Accumulation: Dose, Dose Interval, and Plasma Level Fluctuation
Change in Elimination Characteristics during Drug Therapy
Quantification of Drug Action
Dose-Response Relationship
Concentration-Effect Relationship
Concentration-Effect Curves
Drug-Receptor Interaction
Concentration-Binding Curves
Types of Binding Forces
Covalent Bonding
Noncovalent Bonding
Models of the Molecular Mechanism of Agonist/Antagonist Action
Other Forms of Antagonism
Enantioselectivity of Drug Action
Receptor Types
Mode of Operation of G-Protein- coupled Receptors
Time Course of Plasma Concentration and Effect
Adverse Drug Effects
Adverse Drug Effects, Side Effects
Causes of Adverse Effects
Drug Allergy
Cutaneous Reactions
Drug Toxicity in Pregnancy and Lactation
Genetic Variation of Drug Effects
Drug-independent Effects
Systems Pharmacology
Drugs Acting on the Sympathetic Nervous System
Sympathetic Nervous System
Structure of the Sympathetic Nervous System
Adrenergic Synapse
Adrenoceptor Subtypes and Catecholamine Actions
Smooth Muscle Effects
Metabolic Effects
Receptor Desensitization
Structure-Activity Relationships of Sympathomimetics
Indirect Sympathomimetics
�-Sympathomimetics, �-Sympatholytics
Drugs Acting on the Parasympathetic Nervous System
Parasympathetic Nervous System
Cholinergic Synapse
Biogenic Amines
Histamine Effects and Their Pharmacological Properties
Occurrence and Functions
Promoters of Serotonin Effects
Serotonin Inhibitors
Substance P
Amino Acids
Organic Nitrates
Calcium Antagonists
Dihydropyridine Derivatives
Verapamil and Other Catamphiphilic Ca<sup>2+</sup> Antagonists
Inhibitors of the Renin-Angiotensin-Aldosterone System
Drugs Acting on Smooth Muscle
Drugs Used to Influence Smooth-Muscle Organs
Cardiac Drugs
Cardiac Glycosides
Antiarrhythmic Drugs
Drugs for Selective Control of Sinoatrial and AV Nodes
Nonspecific Drug Actions on Impulse Generation and Propagation
Electrophysiological Actions of Antiarrhythmics of the Na<sup>+</sup> Channel-blocking Type
Drugs for the Treatment of Anemias
Vitamin B<sub>12</sub>
Folic Acid
Iron Deficiency Anemia
Prophylaxis and Therapy of Thrombosis
Vitamin K Antagonists and Vitamin K
Possibilities for Interaction
Hirudin and Derivatives
Inhibitors of Platelet Aggregation
Presystemic Effect of ASA
Plasma Volume Expanders
Drugs Used in Hyperlipoproteinemias
Lipid-lowering Agents
Diuretics-An Overview
NaCl Reabsorption in the Kidney
Aquaporins (AQP)
Osmotic Diuretics
Diuretics of the Sulfonamide Type
Potassium-sparing Diuretics
Vasopressin and Derivatives
Water and Electrolyte Disorders
Disorders of Na<sup>+</sup> Homeostasis
Disorders of K<sup>+</sup> Homeostasis
Gastrointestinal Tract
Therapy of Gastric and Duodenal Ulcers
Treatment of Hyperacidity
Antidiarrheal Agents
Drugs Affecting the Motor System
Drugs Affecting Motor Function
Central Muscle Relaxants and Toxins
Muscle Relaxants
Depolarizing Muscle Relaxants
Nondepolarizing Muscle Relaxants
Influencing the Contractile System
Drugs for the Suppression of Pain (Analgesics)
Pain Mechanisms and Pathways
Antipyretic Analgesics vs. NSAIDs
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Cyclooxygenase (COX) Inhibitors
Local Anesthetics
Opioids = Opiates
Drugs Acting on the Central Nervous System
General Anesthesia and General Anesthetic Drugs
Inhalational Anesthetics
Injectable Anesthetics
Benzodiazepine Antagonist
Pharmacokinetics of Benzodiazepines
Therapy of Depressive Illness
Agents to Treat Manic States
Therapy of Schizophrenia
Hypothalamic and Hypophyseal Hormones
Thyroid Hormone Therapy
Hyperthyroidism and Antithyroid Drugs
Glucocorticoid Therapy
Replacement Therapy
Pharmacodynamic Therapy with Glucocorticoids
Androgens, Anabolic Steroids, Antiandrogens
Inhibitory Principles
Follicular Growth and Ovulation, Estrogen and Progestin Production
Oral Contraceptives
Antiestrogen and Antiprogestin Active Principles
Aromatase Inhibitors
Diabetes Mellitus
Variations in Dosage Form
Variation in Amino Acid Sequence
Treatment of Insulin-dependent Diabetes Mellitus
Undesirable Effects
Treatment of Type II Diabetes Mellitus
Oral Antidiabetics
Drugs for Maintaining Calcium Homestasis
Antibacterial Drugs
Drugs for Treating Bacterial Infections
Inhibitors of Cell Wall Synthesis
Pore Formers
Inhibitors of Tetrahydrofolate Synthesis
Inhibitors of DNA Function
Inhibitors of Protein Synthesis
Drugs for Treating Mycobacterial Infections
Antitubercular Drugs
Antileprotic Drugs
Antifungal Drugs
Drugs Used in the Treatment of Fungal Infections
Antiviral Drugs
Pharmacotherapy of Viral Infections
Drugs for the Treatment of HIV
Inhibitors of Reverse Transcriptase-Nucleoside Agents
Nonnucleoside Inhibitors
HIV protease Inhibitors
Reserve Drugs
Antiparasitic Drugs
Drugs for Treating Endoparasitic and Ectoparasitic Infestations
Other Tropical Diseases
Anticancer Drugs
Chemotherapy of Malignant Tumors
Interference with Cell Proliferation Signaling Pathways
Special Antineoplastic Drug Actions
Mechanisms of Resistance to Cytostatics
Immune Modulators
Inhibition of Immune Responses
Calcineurin Inhibitors, Sirolimus
Inhibitors of Leukocyte Migration
Antidotes and Treatment of Poisonings
�Recreational� Drugs
Psychotomimetics (Psychedelics, Hallucinogens)
Actions of Nicotine
Localization of Nicotinic ACh Receptors
Effects of Nicotine on Body Function
Aids for Smoking Cessation
Consequences of Tobacco Smoking
Alcohol Abuse
Therapy of Selected Diseases
Angina Pectoris
Antianginal Drugs
Acute Coronary Syndrome-Myocardial Infarction
Congestive Heart Failure
Septic Shock
Antiparkinsonian Drugs
Treatment of Migraine
Sleep Disorders and Hypnotics
Local Treatment of Glaucoma
Obesity-Sequelae and Therapeutic Approaches
Atopy and Antiallergic Therapy
Bronchial Asthma
Rheumatoid Arthritis
Chronic Inflammatory Bowel Disease
Further Reading
Drug Indexes
Trade Name/Drug Name
Drug Name/Trade Name
Subject Index
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