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| About the Author | |
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| Dedication | |
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| Preface to 1st & 2nd Editions and Acknowledgements | |
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| Preface to 3rd Edition (Book Description) | |
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| Introduction | |
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| Children With Real Medical Illnesses | |
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| A Message of Hope | |
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| Defeat Autism Now! | |
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| What Can a Parent Expect From Biomedical Interventions? | |
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| My Personal and Professional Involvement in the Bio-Medicine of Autism | |
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| My Most Challenging Case | |
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| Causation Models | |
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| The Worldwide Autism Spectrum Disorder (ASD) Epidemic | |
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| Definition of ASD and Incidence of Classic vs. Regressive Autism | |
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| What Causes Autism and Other ASDs? | |
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| Simply Genetic? | |
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| The Toxic Chemical Model | |
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| The Heavy Metal Contamination Model | |
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| Vaccinations | |
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| The Auto-immunity/Allergy Model | |
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| The Viral Model | |
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| The Gluten/Casein, Enzyme Deficiency and Yeast Overgrowth Model | |
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| The Metallothionein Theory | |
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| How Models of Causation Lead to Treatments That Work | |
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| Gastrointestinal Pathology-Nutritional Deficiencies | |
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| Nutritional Deficiency as a Common Denominator | |
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| Causes of Gastrointestinal Problems in ASD Children | |
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| How the Immune and GI Systems Interact | |
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| How Yeast Overgrowth Can Injure the Gastrointestinal System | |
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| "Leaky Gut", Increased Permeability of the Intestinal Mucosa and Malabsorption | |
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| Further Notes on the Mercury/Vaccine Connection | |
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| Putting the Puzzle Pieces Together | |
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| Impaired Detoxification, Toxic Accumulations, and Politics | |
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| Toxic Threats to Child Development | |
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| The Mechanism of Heavy Metal Toxicity | |
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| Specific Heavy Metals: Lead and Mercury | |
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| Lead | |
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| Mercury | |
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| Mercury in Vaccines | |
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| The Saga of Several Autism Parents and "Parent Power" | |
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| Clinical and Diagnostic Evaluation | |
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| Biomedical Evaluation | |
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| Family and Medical History | |
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| Pre-testing Considerations | |
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| New Diagnostics in ASD Based on Screening | |
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| Initial Strategies in Test Evaluation | |
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| More Tests, New Philosophy | |
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| Parents, Doctors, and Testing Philosophy | |
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| Descriptions of Specific Laboratory Tests | |
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| Necessary Preliminary Screening Tests | |
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| Complete Blood Count (CBC) with Differential and Platelets | |
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| Comprehensive Metabolic Panel | |
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| Thyroid Panel | |
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| Urinalysis | |
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| Hair Analysis (Part of Heavy Metal Screening) | |
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| Specialized Laboratory Tests as Individually Indicated | |
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| Urinary Peptide Tests for Casein and Gluten | |
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| Organic Acid Test (OAT-urine) | |
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| 90-Food IgG Antibodies Test (Serum) | |
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| Amino Acids (Plasma) | |
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| Comprehensive Microbial Digestive Stool Analysis | |
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| Fatty Acid Analysis (Plasma) | |
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| Tests for Metallothionein Dysfunction | |
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| Laboratory Testing in Chelation Therapy | |
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| Immunology Testing | |
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| Which Laboratories to Use | |
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| Gastrointestinal Healing | |
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| Gastrointestinal Health is a Key Issue | |
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| Treatments That Can Be Implemented by Parents | |
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| The GF/CF/SF (Gluten, Casein, Soy Free) Diet | |
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| How to Start the Diet | |
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| Where to Get Help | |
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| Enzymes | |
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| Probiotics | |
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| Basic Nutrient Supplementation | |
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| Gastrointestinal Treatments That Require Physician Participation | |
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| Anti-fungal Treatment | |
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| Other Gut Pathogens and Treatments | |
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| The Secretin Story | |
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| Summary-Gut Health and Healing | |
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| Feeding the Starving Brain | |
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| Vital Nutrients | |
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| Nutritional Deficiencies Identified in Our Children | |
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| The Use of Vital Nutrients | |
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| Primary Recommended Supplements | |
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| The Rationale Behind the Use of Specific Nutrients | |
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| B6 and Magnesium | |
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| Zinc | |
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| Calcium | |
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| Selenium | |
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| Vitamin A and High-Dose Vitamin A Protocol | |
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| Vitamins C and E | |
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| Essential Fatty Acids | |
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| DMG and TMG | |
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| B-Vitamins | |
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| Amino Acids | |
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| Additional Minerals | |
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| Nutrient Interactions | |
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| Testing for Nutritional Deficiencies | |
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| Parents Say Nutrients Help Their Children | |
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| Removing the Heavy Metals | |
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| Heavy Metal Toxicity | |
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| A Practical Approach to the Removal of Mercury | |
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| Pre-Chelation Testing | |
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| Hair Analysis | |
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| Porphyrin Testing | |
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| Pre- and Post-Challenge Urine Toxic Elements Test | |
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| RBC Essential Elements | |
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| Cysteine | |
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| Gut Readiness Before Starting Chelation | |
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| Organic Acid Test (OAT) | |
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| Comprehensive Microbial Digestive Stool Analysis | |
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| Nutrient/Mineralization Readiness | |
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| Heavy Metal Detoxification per 2005 Defeat Autism Now! Consensus, Summary | |
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| Phase I, DMSA (Di-mercaptosuccinic Acid) Dosages and Timing | |
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| Dosages, DMSA | |
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| Lab Monitoring | |
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| Readiness for Second Phase: Adding A-lipoic Acid (ALA) | |
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| Second Phase, Laboratory Monitoring | |
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| Completion of Chelation Process | |
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| Alternative Detoxification Treatment | |
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| Allithiamine: Transdermal Thiamine Tetrahydrofurfuryl Disulfide (TTFD) | |
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| Summary | |
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| General Comments on Detoxification Treatment | |
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| Immunity, Autoimmunity and Viruses | |
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| An Overview of Immune Dysregulation in ASD Children | |
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| Genetics | |
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| Immune Abnormalities | |
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| Autoimmunity and Autism | |
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| Pathogens and Autoimmunity | |
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| Gastrointestinal Disease and Autism Spectrum Disorder | |
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| MMR and Developmental Regression | |
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| Fungal Infections and the Immune System | |
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| Atypical Elevations of Common Viral Titers | |
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| Allergy and Immunity | |
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| Chronic Low-grade Infections | |
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| Diagnostics-Immune Testing | |
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| Comprehensive (Herpes) Viral Screen | |
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| Myelin Basic Protein (MBP) Antibodies | |
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| Case History-Suzie | |
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| Anti-Viral and Immune Treatment Issues | |
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| Treatments to Enhance the Immune System | |
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| Immunomodulators and Immune Boosters | |
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| Natural Immunomodulators | |
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| Probiotics as Immunomodulators | |
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| Glutathione, or GSH | |
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| IVIG (Intravenous Immune Globulin [Human]) | |
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| High-Dose Vitamin A Protocol | |
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| Prescription Immune-Enhancing Medications | |
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| Anti-viral Prescription Medications | |
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| A Parent's Story-Stan Kurtz | |
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| Viral/Immune Treatment Summary | |
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| Hbot-Hyperbaric Oxygen Therapy for Autism Spectrum Disorders | |
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| Foreword | |
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| History and Description | |
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| Benefits | |
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| Side Effects | |
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| Multiple Mechanisms of Action | |
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| Basic Principles and Safe Protocols | |
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| Questions and Concerns | |
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| Summary | |
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| Selected Bibliography | |
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| Latest Developments | |
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| Methylation | |
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| Genetic Testing for Methylation Defects | |
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| Actos | |
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| Low-Dose Naltrexone | |
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| Low Oxalate Diet | |
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| Mitochondrial Dysfunction & Treatments | |
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| Introduction | |
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| Treatment Issues | |
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| Drugs and Medical States That Negatively Affect Mitochondria | |
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| Testing for Mitochondrial Dysfunction | |
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| Current Mainstream Medical Treatment Strategies for Mitochondrial Disorder | |
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| Mitochondrially Targeted Nutrients to Treat ASD | |
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| Important Nutrients for Supporting Mitochondrial Health | |
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| Starving Brains, Starving Hearts, What Does It All Mean? | |
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| Messages | |
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| Jaquelyn, Chelsey and Elizabeth | |
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| Awareness of Subtle Relationships | |
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| Final Words | |
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| Appendices | |
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| Progress in Gastrointestinal Research and Its Relationship to Immunity in Autism | |
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| Autism, Metals, and the Mercury in Vaccines, and the alternative version of the "Autism/Mercury Paper" | |
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| Introductory Comments | |
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| Intra-Body Toxins | |
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| Mitochondrial Concerns | |
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| Implications for Medicine, Education and the Environment | |
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| A Poetic Version of our Journey with Chelsey | |
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| Index | |