#60;b#62;Chris Williams #60;/b#62;is Clinical Director of the Bristol Haematology and Oncology Centre, Bristol, UK and former Editor of the Cochrane Oncology Review Group#60;br#62;#60;p#62;#60;b#62;Paul Cornes#60;/b#62; is Consultant Clinical Oncologist at the Bristol Haematology and Oncology Centre and was previously at the Royal Marsden Hospital in London, UK