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| List of contributors | |
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| Foreword | |
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| Introduction | |
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| Epidemiology and Outcomes | |
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| The epidemiology of critical illness brain dysfunction | |
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| Cognitive dysfunction following critical illness | |
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| Psychiatric disorders following critical illnesses | |
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| Functional status and quality of life after critical illness | |
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| Delirium and dementia: unraveling the complex relationship | |
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| Behavioral Neurology in the ICU | |
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| Cognitive reserve | |
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| Neurology of consciousness impairments | |
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| Mechanisms of attention and attentional impairment | |
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| Neurology of sleep and sleep disorders | |
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| Neural basis of fear and anxiety | |
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| Biological Mechanisms | |
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| Experimental models of cognitive dysfunction in infection and critical illness | |
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| Neurobiological effects of systemic physiological and metabolic insults | |
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| Cerebral ischemia and reperfusion | |
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| Brain perfusion and autoregulation in systemic critical illness | |
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| Delirium and neurotransmitter dysfunction | |
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| Neuromodulatory and neurotoxic effects of sedative agents | |
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| Neuroimmunological cross-talk in critical illness | |
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| Inflammatory mechanisms in chronic neurodegenerative disease: the impact of microglia priming | |
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| The neuroendocrine response to critical illness | |
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| Autonomic dysfunction in SIRS and sepsis | |
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| Sepsis-induced neuronal dysfunction and death | |
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| Neuroimmunomodulation in sepsis | |
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| Diagnosis of Brain Dysfunction | |
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| Clinical neurological assessment of the critically ill patient | |
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| Bedside assessment of delirium in critically ill patients | |
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| Electroencephalography and evoked potentials in critically ill patients | |
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| Neuroimaging of delirium | |
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| Preventative and Therapeutic Interventions | |
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| Environmental modification | |
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| New paradigms in sedation of the critically ill patient | |
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| Pharmacological management of delirium | |
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| Pharmacogenomics and cerebral dysfunction | |
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| Early physical and occupational therapy | |
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| Rehabilitation after critical illness | |
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| Clinical Encephalopathy Syndromes | |
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| Drug-induced encephalopathy | |
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| Metabolic encephalopathies: inborn errors of metabolism causing encephalopathies in adults | |
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| Encephalopathy associated with alcohol or drug withdrawal | |
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| Posterior reversible encephalopathy syndrome (PRES): the essential elements | |
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| Hypoxic-ischemic encephalopathy | |
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| Sepsis-associated encephalopathy | |
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| Seizures and status epilepticus in critical illness | |
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| Encephalopathy and coma in acute and chronic liver failure | |
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| Neurological complications of cardiac surgery: stroke, encephalopathy, and cognitive decline | |
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| Glossary | |
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| Index | |
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| Color plate section is between pp. 320 and 321. | |