Good Germs, Bad Germs Health and Survival in a Bacterial World

ISBN-10: 0809050633

ISBN-13: 9780809050635

Edition: 2007

Authors: Jessica Snyder Sachs, Jessica S. Sachs

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Making Peace with Microbes Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. "Good Germs, Bad Germs" addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.
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Book details

List price: $25.00
Copyright year: 2007
Publisher: Farrar, Straus & Giroux
Publication date: 10/16/2007
Binding: Hardcover
Pages: 304
Size: 6.00" wide x 9.25" long x 1.00" tall
Weight: 1.144
Language: English

Seven Key Terms and Conventionsp. ix
Prologue: A Good War Gone Bad
Ricky's Storyp. 3
Daniel's Storyp. 7
Revenge of the Microbes?p. 9
The War on Germs
From Miasmas to Microbesp. 15
Germ Theory Rebornp. 20
The Sanitariansp. 26
The Search for Magic Bulletsp. 29
Life on Man
The Body as Ecosystemp. 35
Into the Mouths of Babesp. 37
Life on the Surfacep. 41
Life on the Insidep. 44
Bugs in Spacep. 45
Where No Biologist Has Gone Beforep. 49
The Inner Tube of Lifep. 52
Who's the Boss?p. 59
A New Window Opensp. 64
Stealth Infections or Innocent Bystanders?p. 67
Too Clean?
Hair Triggerp. 73
From Hippocrates to the Hygiene Hypothesisp. 76
A History of Self-Destructionp. 81
Children in the Cowshedp. 83
Teaching Tolerancep. 87
Innate Immunityp. 89
The Dirt Vaccinep. 91
Old Friendsp. 97
Beyond Immunityp. 101
Bugs on Drugs
A Killer in the Nurseryp. 105
An End to Bacterial Disease?p. 109
Microscopic Mating Gamesp. 111
The Bacterial Superorganismp. 115
Danger Ignoredp. 116
Old Habits, New Insightsp. 120
Out of the Hospital and into Our Daily Livesp. 125
The Reservoir Withinp. 131
Resistance by the Shovelp. 136
Down on the Farmp. 141
The Antibiotic Paradoxp. 148
Fighting Smarter, Not Harder
The Good Old Days?p. 151
Preserving Antibiotics: Less Is Morep. 154
Homing In on the Enemyp. 158
Drugs with On-Off Switchesp. 163
Silencing Resistancep. 165
Farming Out Resistancep. 168
Beyond Antibiotics: New Ways to Killp. 170
Cocoons and Frog Slimep. 176
Beyond Lethal Force - Defang, Deflect, and Deploy
Drugs That Disarmp. 185
Vaccines - Forewarned Is Forearmedp. 189
Domesticate and Deployp. 193
Prescription Probioticsp. 196
Fighting Fire with Firep. 199
A Superhero for the Mouthp. 203
Transgenic Probioticsp. 205
Probiotics for Livestockp. 212
A Second Neolithic Revolutionp. 214
Fixing the Patient
The Dragon Withinp. 219
Enhancing the Bionic Humanp. 225
From Sepsis to Chronic Inflammationp. 228
Immunobug Immunodrugsp. 232
Tweaking the Bugp. 233
Into the Futurep. 234
Coda: Embracing the Microbiomep. 235
Notesp. 239
Further Readingp. 273
Acknowledgmentsp. 275
Indexp. 277
Table of Contents provided by Ingram. All Rights Reserved.
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