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Basic Principles | |
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Introduction to the Nervous System | |
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Nerve Cells and Nerve Fibers | |
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Organization of Cells and Fibers in the Nervous System | |
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Functionally Defined Fiber Groups in the Peripheral Nerves | |
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Overview of the Gross Anatomy of the Nervous System | |
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Internal Anatomy of the Spinal Cord | |
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Development of the Nervous System | |
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Physiology of Nerve Cells | |
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Resting Membrane Potential | |
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Ion Channels Control Membrane Potential | |
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Action Potential | |
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Action Current | |
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Afterpotentials and Refractory Periods Follow the Action Potential | |
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Synapses | |
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Neuromuscular Junction | |
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Peripheral Nervous System | |
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Fibers of the spinal Nerves | |
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Functional Classification | |
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Physiologic Classification | |
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Spinal Reflexes and Muscle Tone | |
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Spinal Reflexes | |
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Muscle Spindles | |
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Alpha, Beta, and Gamma Motoneurons of the Spinal Cord | |
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Stretch Reflex | |
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Golgi Tendon Organs and Their Reflexes | |
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Muscle Tone | |
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Reflexes of Cutaneous Origin | |
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Autonomic Nervous System | |
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The Autonomic Nervous System Has Two Divisions | |
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Sympathetic Nervous System | |
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Parasympathetic Nervous System | |
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Autonomic Innervation of the Genitourinary System | |
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Autonomic Reflexes of Other Pelvic Viscera | |
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Ascending and Descending Pathways | |
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Pain and Temperature | |
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Somatic Sensation | |
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Overview of the Pathways for Pain, Thermal Sense, and Touch | |
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Dorsal Roots of the Spinal Nerves Supply Dermatomes | |
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Adjacent Spinal Nerves Form Peripheral Nerves | |
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Pain-Temperature Pathways | |
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Perception of Pain | |
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Temperature Sense | |
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Visceral Pain Pathways and Referred Pain | |
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Effect of Cutting the Spinothalamic Tract | |
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Sensory Effects of Dorsal Root Irritation | |
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Endogenous Analgesia | |
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Central Pain (Thalamic Syndrome) | |
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Proprioception, Touch, and Tactile Discrimination | |
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Central Nervous System Pathways | |
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Physiologic Aspects of Tactile Discrimination | |
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Effect of Spinal Cord Lesions on Touch Sensation | |
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Motor Pathways | |
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Motor Areas of the Cerebral Cortex | |
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Descending Fibers from the Cerebral Cortex and Brain Stem Influence Motor Activity | |
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Role of Lateral, Medial, and Propriospinal Pathways in Spinal Cord Function | |
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Lesions of the Peripheral Nerves, Spinal Nerve Roots, and Spinal Cord | |
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Degeneration and Regeneration of Nerve Cells and Fibers after Injury | |
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Clinical Consequences of Peripheral Nerve Lesions | |
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Lower Motoneuron Lesions: Hypotonic Paralysis of Muscles | |
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Lesions of Dorsal Roots | |
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Upper Motoneuron Lesions: Spastic Paralysis of Muscles | |
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Abnormal Reflexes Associated with Lesions of the Motor Pathway | |
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Transection of the Spinal Cord | |
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Hemisection of the Spinal Cord (Brown-Sequard Syndrome) | |
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Lesions of the Central Gray Matter of the Spinal Cord | |
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Lesions Involving the Ventral Horns and the Corticospinal Tracts | |
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Lesions Involving Dorsal and Lateral Funiculi | |
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Thrombosis of the Anterior Spinal Artery | |
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Tumors of the Spinal Cord | |
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Brain Stem and Cerebellum | |
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Organization of the Brain Stem and Cranial Nerves | |
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Surface Anatomy of the Brain Stem | |
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Internal Structures at the Transition from Spinal Cord to Brain Stem | |
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Classification of Cranial Nerve Nuclei and Fibers according to their Functions | |
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Functionally Distinct Cranial Nerve Cell Columns | |
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Reticular Formation | |
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Atlas of the Brain Stem: Transverse Sections | |
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Blood Supply to the Brain Stem and Cerebellum | |
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Cranial Nerves of the Medulla | |
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Hypoglossal Nerve (XII) | |
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Accessory Nerve (XI) | |
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Vagal System: Nervus Intermedius (VII), Glossopharyngeal (IX), Vagus (X) and Cranial Accessory (XI) Nerves | |
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Cranial Nerves of the Pons and Midbrain | |
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Abducens Nerve (VI) | |
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Trochlear Nerve (IV) | |
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Oculomotor Nerve (III) | |
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Facial Nerve (VII) | |
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Trigeminal Nerve (V) | |
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Lesions of the Brain Stem | |
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Principles of Localization | |
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Lesions of the Medulla | |
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Lesions of the Pons | |
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Lesions of the Midbrain | |
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Brain Stem Lesions Causing Coma and "Locked-in" Syndrome | |
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Hearing | |
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Ear | |
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Central Auditory Pathways | |
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Diagnosing Hearing Deficits from Nerve Damage and from Conductive Defects | |
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Auditory Reflexes | |
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Vestibular System | |
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Vestibular Portion of the Inner Ear | |
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Vestibular Nerve and Its Central Connections | |
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Vestibulocerebellar Connections | |
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Vestibulospinal Tracts | |
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Vestibulo-ocular Systems | |
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Vestibulothalamocortical Pathway | |
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Sensory Aspects of Vestibular Stimulation | |
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Cerebellum | |
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Overview of Cerebellar Function | |
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Cerebellar Anatomy | |
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Peduncles | |
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Major Circuits | |
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Integration of the Cerebellum and Cerebral Cortex in Movement and Cognition | |
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Clinical Signs of Cerebellar Dysfunction | |
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Diseases | |
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Forebrain | |
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Basal Ganglia | |
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Overview | |
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Components | |
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Connections of the Dorsal Striatum and Pallidum with the Cerebral Cortex | |
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Connections of the Pallidum with the Brain Stem | |
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Ventral Striatum and Pallidum | |
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Function and Dysfunction | |
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Vision | |
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Overview of the Visual Pathways | |
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Retina | |
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Visual Pathways | |
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Information Processing in the Visual Pathways | |
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Effects of Lesions Interrupting the Visual Pathway | |
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Optic Reflexes and Eye Movements | |
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Light Reflexes | |
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Reflexes Associated with the Near-Point Reaction | |
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Disorders of Pupillary Function | |
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Eye Movements | |
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Cerebral Cortex and Thalamocortical Connections | |
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Cerebral Cortex | |
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Cortical Cell Layers: The Basis for Structure and Function Relationships within and between Cortical Areas | |
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Cortical Networks and Information Processing | |
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Thalamus | |
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Thalamocortical Connections | |
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Functional Cortical Regions | |
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Disorders of Cortical Networks | |
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Limbic System | |
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Overview | |
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Telencephalic Limbic System | |
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Hypothalamus | |
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Hypothalamic Functions | |
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Epithalamus | |
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Olfaction | |
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Olfactory Receptors | |
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Olfactory Bulbs and Their Projections | |
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Olfactory Cortical Areas | |
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Damage to Olfactory Structures | |
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Chemical Neuroanatomy | |
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Characteristics of Neurotransmitter Molecules | |
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Functional Characterization of Neurotransmitter Receptors | |
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Acetylcholine | |
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Monoamines | |
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Neuropeptides | |
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Amino Acids | |
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Circulation of Blood and Cerebrospinal Fluid | |
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Cerebral Arteries Supplying the Forebrain | |
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Anterior Circulation | |
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Internal Carotid Artery and Its Branches | |
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Posterior Cerebral Artery and Its Branches | |
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Formation of the Circle of Willis and Its Central Branches | |
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Cerebrospinal Fluid | |
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Formation and Circulation | |
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Composition and Function | |
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Blood-Brain Barrier | |
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Pressure | |
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Approaches to Patients with Neurologic Symptoms | |
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Clinical Evaluation of Neurologic Disorders | |
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Patient History | |
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Physical Examination | |
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Neurologic Examination | |
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Neurologic Diagnostic Tests | |
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Cerebrospinal Fluid Analysis | |
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Electroencephalography and Evoked-Potential Studies | |
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Nerve Conduction Studies, Electromyography, and Muscle and Nerve Biopsy | |
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Anatomic Imaging Studies | |
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Physiologic Imaging Studies | |
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Suggested Readings | |
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Index | |