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| Foreword | |
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| Introduction: Why is genomics important for nurses to utilize in their practice? | |
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| Connecting Genomics to Biology | |
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| Introduction: Genetics Old and New | |
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| Elucidating the Structure and Function of the Human Genome | |
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| Human Genome Discoveries | |
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| Chromosomes, Genes, and DNA: Basic Human Genetics Terminology | |
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| DNA and RNA: How Proteins Are Made | |
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| Genetic Variation and Basic Patterns of Inheritance | |
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| New Genomics and Biology | |
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| Nursing Implications: The Importance of Family History in Assessment, Planning, Diagnosis, and Treatment | |
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| Summary | |
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| Chapter Activities | |
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| Connecting Genomics to Practice | |
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| Family History as a Tool | |
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| Variation in the Human Genome | |
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| Family History Tools | |
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| Ethical Issues and Family History | |
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| Genetics and Genomics in Practice | |
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| Resources for Public Information | |
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| Summary | |
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| Chapter Activities | |
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| Connecting Genomics to Health Benefits | |
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| Introduction | |
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| Genetic Approaches to Prevention and Early Detection | |
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| Genetic Testing | |
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| Disease and Drug Response | |
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| Therapeutic Approaches | |
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| Health Modifiers | |
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| Conveying Genetic Risk Information | |
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| Monitoring for Residual Disease and Medical Surveillance | |
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| Health Care Resources and Systems | |
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| Summary | |
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| Chapter Activities | |
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| Connecting Genomics to Health Benefits: Genetic Testing | |
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| Introduction | |
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| Genetic Testing: What it is and How it is Used Clinically | |
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| Genetic Testing Defined | |
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| Types of Genetic Testing | |
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| Clinical Genetic Tests | |
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| Research Genetic Tests | |
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| Oversight of Genetic Testing | |
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| Information Provided by Genetic Testing | |
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| Clinical Uses of Genetic Testing: Newborn Screening, Carrier Testing, Prenatal Screening and Diagnosis | |
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| Newborn Screening | |
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| Family Education and Support | |
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| Carrier Testing | |
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| Prenatal Screening and Diagnosis | |
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| Potential Risk of Genetic Testing | |
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| Cultural and Economic Issues and Genetic Testing | |
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| Summary | |
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| Chapter Activities | |
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| Connecting Genomics to Health Outcomes: Pharmacogenetics and Pharmacogenomics | |
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| Introduction | |
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| Pharmacogenetics and Pharmacogenomics | |
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| Genetic Mechanisms and Variable Drug Response | |
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| Pharmacokinetics | |
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| Pharmacodynamics | |
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| Clinical Applications of Pharmacogenetics | |
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| Gene-Environment Interactions and Clinical Interventions | |
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| Nursing Implications | |
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| Nursing Roles | |
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| Ethical and Societal Issues | |
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| Summary | |
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| Chapter Activities | |
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| Putting the Pieces Together: How I Learned of the Genetic Condition in My Family | |
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| Introduction | |
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| Indications for Making a Genetics Referral: Putting the Pieces Together | |
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| A Nursing Framework for Making a Genetics Referral | |
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| Nursing Assessments and Genetic Referrals | |
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| Finding Peer Support | |
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| Summary | |
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| Chapter Activities | |
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| Commentary: "Breaking the News" Talking with Parents about Their Child's Birth Defect or Genetic Condition, Physician, Alan Guttmacher, MD | |
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| Finding What I Need | |
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| Introduction | |
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| How Genetics Professionals Became a Part of My Life | |
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| Genetics Counseling and Evaluation: What Is It and Who Are the Providers? | |
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| Genetics Specialists: Who They are and What They Do | |
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| Nursing and Genetic Education and Counseling | |
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| Future Models for Genetic Counseling and Evaluation | |
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| Summary | |
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| Chapter Activities | |
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| Commentary: Without a Bigger Team, Our "Genomics" Cup Will Runneth Over, Genetic Counselor, Don Hadley, MS, OGC | |
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| Transitions and New Understandings: How Genetics Has Transformed My Life | |
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| Introduction: The Impact of Genetic Information | |
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| Transitions and New Understandings: Genetics and My Personal Life | |
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| Before Testing: How I Coped | |
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| To Test or Not To Test | |
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| How My Test Result Affected Me | |
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| More Decisions: Sharing My Genetic Information | |
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| New Roles and Relationships: Genetics and My Family | |
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| Nursing Implications | |
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| Summary | |
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| Chapter Activities | |
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| Commentary: The Role of the Psychologist in Genetics Clinical Care, Psychologist, Andrea Farkas Patenaude, PhD | |
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| Connecting Genomics to Society | |
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| Introduction | |
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| Genomic Data and Race, Ethnicity, and Culture | |
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| Genomics and the Concept of "Self" | |
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| Genomics and the Family: Traits and Behaviors | |
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| Genomics and Community Identity | |
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| Genomics, Race, Ethnicity, and Research | |
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| Ethical Boundaries and Use of Genomics | |
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| Translation of Research to Policy: Integration of Genetics and Genomics | |
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| Implications for Nursing: Transcultural Nursing | |
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| Chapter Activities | |
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| Connecting Genomics to Society: Spirituality and Religious Traditions | |
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| Introduction | |
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| Genomics and the Concept of Normal: What is Normal? | |
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| Genomics and the Concept of Soul: When Does Life Begin? | |
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| Genomics and Identity: What Does It Mean to Be Human? | |
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| Religious Boundaries and Use of Genomics: What Can We Do? What Should We Do? | |
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| Gene Therapy: Is It All in the Genes? | |
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| Cloning | |
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| Stem Cell Research | |
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| Translation of Religion to Policy: Integration of Genetics and Genomics | |
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| Implications for Nursing: Spirituality in Care | |
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| How Then Should We Face the Future? | |
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| Chapter Activities | |
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| My Hopes and Fears: How I Feel about Genetic Research | |
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| Introduction | |
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| Genetic Research | |
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| Genetc Testing Research | |
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| Genetic Mapping Research | |
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| Treatment Research: Clinical Trials | |
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| Pharmacogenetic Research | |
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| Ethical and Social Considerations with Genetic Testing and Treatment Research | |
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| Genetics Research and Racially or Ethnically Diverse Populations | |
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| Genetic Testing and Community Research | |
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| Summary: Implications for Nurses | |
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| Chapter Activities | |
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| Braving New Frontiers: What Is My Future with My Genetic Condition? | |
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| Introduction | |
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| Profound Change | |
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| Power | |
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| Possibilities | |
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| Policy | |
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| Patience | |
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| Persuaded | |
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| Professionals | |
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| Public Perception | |
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| Public Health | |
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| Preventive | |
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| Predictive | |
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| Perplexities | |
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| Performance | |
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| Promise | |
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| Priorities | |
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| Passionate | |
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| Chapter Activities | |
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| Commentary: Kevin Lewis, Chairman of the Board, Colon Cancer Alliance | |
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| Integration of Genomics to Improve Health Care | |
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| Introduction | |
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| Research Advances and Integration of Genomics into Health Care | |
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| HapMap | |
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| Genomics and Future Applications | |
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| Genomics and Nursing Practice: Expanding Roles for Nurses | |
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| Educating Nurses to Face the Challenge | |
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| Research Directions | |
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| Moving Forward | |
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| Chapter Activities | |
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| Commentary: Summary of the Contribution of the Credentialing Process to Assurance of Quality Nursing Care That Integrates Genetics/Genomics, Rita Black Monsen, DSN, MPH, RN | |
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| Genomics Resources for Nurses | |
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| The Nursing Workforce | |
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| Nurses and Genomics Resources | |
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| Professional Nursing Societies: Genetics Resources for Nurses | |
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| New Information Technologies and Genomics Resources | |
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| Chapter Activities | |
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| Addendum: NCHPEG Competencies | |
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| Purpose | |
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| Implementation | |
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| Recommendations | |
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| References | |
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| Acknowledgments | |
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| NCHPEG Member Organizations | |
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| Index | |