Physics in Nuclear Medicine

ISBN-10: 072168341X

ISBN-13: 9780721683416

Edition: 3rd 2003 (Revised)

Authors: Simon R. Cherry, James A. Sorenson, Michael E. Phelps

List price: $122.95
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In this work, the authors provide up-to-date, comprehensive information on the physics underlying modern nuclear medicine and imaging using radioactively labelled tracers. Examples are presented with solutions worked out in step-by-step detail, illustrating important concepts and calculations.
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Book details

List price: $122.95
Edition: 3rd
Copyright year: 2003
Publisher: Elsevier - Health Sciences Division
Publication date: 8/12/2003
Binding: Hardcover
Pages: 544
Size: 7.50" wide x 10.75" long x 1.00" tall
Weight: 3.080
Language: English

What Is Nuclear Medicine?
Fundamental Concepts
The Power of Nuclear Medicine
Historical Overview
Current Practice of Nuclear Medicine
The Role of Physics in Nuclear Medicine
Basic Atomic and Nuclear Physics
Quantities and Units
The Nucleus
Modes of Radioactive Decay
General Concepts
Chemistry and Radioactivity
Decay by [beta superscript -] Emission
Decay by ([beta superscript -], [gamma]) Emission
Isomeric Transition (IT) and Internal Conversion (IC)
Electron Capture (EC) and (EC, [gamma]) Decay
Positron ([beta superscript +]) and ([beta superscript +], [gamma]) Decay
Competitive [beta superscript +] and EC Decay
Decay by [alpha] Emission and by Nuclear, Fission
Decay Modes and the Line of Stability
Sources of Information on Radionuclides
Decay of Radioactivity
Exponential Decay
Methods for Determining Decay Factors
Image-Frame Decay Corrections
Specific Activity
Decay of a Mixed Radionuclide Sample
Parent-Daughter Decay
Radionuclide and Radiopharmaceutical Production
Reactor-Produced Radionuclides
Accelerator-Produced Radionuclides
Radionuclide Generators
Equations for Radionuclide Production
Radionuclides for Nuclear Medicine
Radiopharmaceutical Preparation
Interaction of Radiation with Matter
Interactions of Charged Particles with Matter
Charged-Particle Ranges
Passage of High-Energy Photons through Matter
Attenuation of Photon Beams
Radiation Detectors
Gas-Filled Detectors
Semiconductor Detectors
Scintillation Detectors
Electronic Instrumentation for Radiation Detection Systems
Pulse-Height Analyzers
Time-to-Amplitude Converters
Digital Counters and Rate Meters
Coincidence Units
High-Voltage Power Supplies
Nuclear Instrument Modules
Cathode Ray Tube
Computer Monitors
Nuclear Counting Statistics
Types of Measurement Error
Nuclear Counting Statistics
Propagation of Errors
Applications of Statistical Analysis
Statistical Tests
Pulse-Height Spectrometry
Basic Principles
Spectrometry with Nal(TI)
Spectrometry with Other Detectors
Problems in Radiation Detection and Measurement
Detection Efficiency
Problems in the Detection and Measurement of [beta] Particles
Dead Time
Quality Assurance for Radiation Measurement Systems
Counting Systems
Nal(TI) Well Counter
Counting with Conventional Nal(TI) Detectors
Liquid Scintillation Counters
Gas-Filled Detectors
Semiconductor Detector Systems
In Vivo Counting Systems
The Gamma Camera: Basic Principles
General Concepts of Radionuclide Imaging
Basic Principles of the Gamma Camera
Types of Gamma Cameras and Their Clinical Uses
The Gamma Camera: Performance Characteristics
Basic Performance Characteristics
Detector Limitations: Nonuniformity and Nonlinearity
Design and Performance Characteristics of Parallel-Hole Collimators
Performance Characteristics of Converging, Diverging, and Pinhole Collimators
Measurements of Gamma Camera Performance
Image Quality in Nuclear Medicine
Basic Methods for Characterizing and Evaluating Image Quality
Spatial Resolution
Observer Performance Studies
Tomographic Reconstruction in Nuclear Medicine
General Concepts, Notation, and Terminology
Backprojection and Fourier-Based Techniques
Image Quality in Fourier Transform and Filtered Backprojection Techniques
Iterative Reconstruction Algorithms
Reconstruction of Fan-Beam and Cone-Beam Data
Single Photon Emission Computed Tomography
SPECT Systems
Practical Implementation of SPECT
Performance Characteristics of SPECT Systems
Clinical Applications of SPECT
Positron Emission Tomography
Annihilation Coincidence Detection
PET Detector and Scanner Designs
Data Acquisition for PET
Data Corrections and Quantitative Aspects of PET
Clinical and Research Applications of PET
Digital Image Processing in Nuclear Medicine
Digital Images
Digital Image-Processing Techniques
Processing Environment
Tracer Kinetic Modeling
Basic Concepts
Tracers and Compartments
Tracer Delivery and Transport
Formulation of a Compartmental Model
Examples of Dynamic Imaging and Tracer Kinetic Models
Internal Radiation Dosimetry
Radiation Dose and Equivalent Dose: Quantities and Units
Calculation of Radiation Dose (MIRD Method)
Radiation Safety and Health Physics
Quantities and Units
Regulations Pertaining to the Use of Radionuclides
Safe Handling of Radioactive Materials
Disposal of Radioactive Waste
Radiation Monitoring
Unit Conversions
Properties of the Elements
Characteristics of Some Medically Important Radionuclides
Mass Attenuation Coefficients for Water, Sodium lodide, BGO, CZT, and Lead
Effective Dose Equivalent (mSv/MBq) and Radiation Absorbed Dose Estimates (mGy/MBq) to Adult Subjects from Selected Internally Administered Radiopharmaceuticals
The Fourier Transform
The FT: What It Represents
Calculating FTs
Some Properties of FTs
Some Examples of FTs
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