| |
| |
| Preface | |
| |
| |
| Common Abbreviations | |
| |
| |
| |
| Introduction | |
| |
| |
| What is pharmacology? | |
| |
| |
| History of pharmacology | |
| |
| |
| Where do drugs come from? | |
| |
| |
| Terminology and drug classification | |
| |
| |
| Drug administration | |
| |
| |
| Routes of drug administration | |
| |
| |
| Drug absorption | |
| |
| |
| Drug distribution | |
| |
| |
| Drug metabolism | |
| |
| |
| Drug excretion | |
| |
| |
| Drugs in the elderly | |
| |
| |
| Drugs in pregnancy and breastfeeding | |
| |
| |
| Summary | |
| |
| |
| |
| How Drugs Work | |
| |
| |
| Intercellular communication | |
| |
| |
| Cellular targets for drug action | |
| |
| |
| Pharmacokinetics | |
| |
| |
| The drug-receptor interaction | |
| |
| |
| The dose-response relationship | |
| |
| |
| Antagonism | |
| |
| |
| Summary | |
| |
| |
| |
| The Role of the Podiatrist in Patient Care | |
| |
| |
| Introduction | |
| |
| |
| Current scope of practice of the podiatrist in the UK | |
| |
| |
| Patient records | |
| |
| |
| Examination, assessment and diagnosis | |
| |
| |
| Clinical assessment and examination | |
| |
| |
| The podiatrist's role in prevention of complications | |
| |
| |
| Patient education | |
| |
| |
| Future role of the podiatrist as a member of the multidisciplinary health care team | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Peripheral Nervous System | |
| |
| |
| Introduction | |
| |
| |
| The neurone | |
| |
| |
| The neuronal action potential | |
| |
| |
| The sensory nervous system | |
| |
| |
| The somatic nervous system | |
| |
| |
| The sympathetic nervous system | |
| |
| |
| The parasympathetic nervous system | |
| |
| |
| Diseases of the peripheral nervous system | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Central Nervous System | |
| |
| |
| Introduction | |
| |
| |
| Alteration of normal CNS function | |
| |
| |
| Diseases of the central nervous system | |
| |
| |
| Parkinson's disease | |
| |
| |
| Epilepsy | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Gastrointestinal System | |
| |
| |
| Introduction | |
| |
| |
| Diseases of the gastrointestinal tract | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Cardiovascular System | |
| |
| |
| Introduction | |
| |
| |
| Diseases of the cardiovascular system | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Respiratory System | |
| |
| |
| Introduction | |
| |
| |
| Diseases of the respiratory system | |
| |
| |
| Summary | |
| |
| |
| |
| Chemotherapeutic Drugs | |
| |
| |
| Introduction | |
| |
| |
| Antibacterial drugs | |
| |
| |
| Classification of bacteria | |
| |
| |
| Bacterial resistance | |
| |
| |
| Folate antagonists | |
| |
| |
| Inhibitors of cell wall synthesis | |
| |
| |
| Protein synthesis inhibitors | |
| |
| |
| Antimycobacterial drugs | |
| |
| |
| Antifungal drugs | |
| |
| |
| Antiviral drugs | |
| |
| |
| Anthelmintics | |
| |
| |
| Antiprotozoal drugs | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Endocrine System | |
| |
| |
| Introduction | |
| |
| |
| Diabetes mellitus | |
| |
| |
| Thyroid disorders | |
| |
| |
| Sex hormones | |
| |
| |
| Osteoporosis | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Urinary Tract | |
| |
| |
| Introduction | |
| |
| |
| The kidneys | |
| |
| |
| Diseases of the kidney | |
| |
| |
| The bladder and urethra | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Reproductive System | |
| |
| |
| The female reproductive system | |
| |
| |
| The male reproductive system | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Musculoskeletal System | |
| |
| |
| Introduction | |
| |
| |
| Treatment of rheumatoid arthritis | |
| |
| |
| The treatment of gout | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Affecting the Eye and Ear | |
| |
| |
| The eye | |
| |
| |
| Diseases of the eye | |
| |
| |
| The ear | |
| |
| |
| Diseases of the ear | |
| |
| |
| Summary | |
| |
| |
| |
| Drugs Acting on the Skin | |
| |
| |
| Introduction | |
| |
| |
| Summary | |
| |
| |
| |
| Local Anaesthetics | |
| |
| |
| Introduction | |
| |
| |
| Summary | |
| |
| |
| |
| Cytotoxic Drugs | |
| |
| |
| Introduction | |
| |
| |
| Strategies for chemotherapy of cancer | |
| |
| |
| Summary | |
| |
| |
| |
| Drug Interactions | |
| |
| |
| Further Reading | |
| |
| |
| Index | |