Neurochemistry of Sleep and Wakefulness

Name: Neurochemistry of Sleep and Wakefulness
Price: 52.95 USD
Availability: InStock
ISBN: 9780521864411

ISBN-10: 0521864410

ISBN-13: 9780521864411

Edition: 2008

Authors: Jaime Monti, Christopher M. Sinton, S. R. Pandi-Perumal

List price: $126.00

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Description:

Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad…

Book details

List price: $126.00
Copyright year: 2008
Publisher: Cambridge University Press
Publication date: 1/17/2008
Binding: Hardcover
Pages: 506
Size: 7.09" wide x 10.00" long x 1.10" tall
Weight: 2.574
Language: English



List of contributors


Preface


Acknowledgements


Abbreviations



The neurochemistry of the states of sleep and wakefulness



Neurochemistry of the preoptic hypothalamic hypnogenic mechanism




Neuroanatomical and neurochemical basis of wakefulness and REM sleep systems




Rapid eye movement sleep regulation by modulation of the noradrenergic system




The influence of neurotransmitters on sleep and wakefulness



Gamma-aminobutyric acid and the regulation of paradoxical, or rapid eye movement, sleep




Acetylcholine modulates sleep and wakefulness: a synaptic perspective




Histamine in the control of sleep-wakefulness




Dopamine in behavioral state control




Glutamate neurotransmission and sleep




Serotonin and sleep-wake regulation




Changing perspectives



Melatonin and its receptors: biological function in circadian sleep-wake regulation




Sleep regulatory factors




Adenosine and sleep-wake regulation




Prostaglandins and the regulation of sleep and wakefulness




Neuropeptides and sleep-wake regulation




Orexins in sleep and wakefulness: rodent models of narcolepsy-cataplexy




The relevance of experimental pharmacology to currently available sleep-wake therapeutics



Index