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Discovering Cell Mechanisms The Creation of Modern Cell Biology

ISBN-10: 0521729440

ISBN-13: 9780521729444

Edition: 2008

Authors: William Bechtel

List price: $31.99
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Description:

Between 1940 and 1970, pioneers in the new field of cell biology discovered the operative parts of cells and their contributions to cell life. Cell biology was a revolutionary science in its own right, but in this book, it also provides fuel for yet another revolution, one that focuses on the very conception of science itself. Laws have traditionally been regarded as the primary vehicle of explanation, but in the emerging philosophy of science it is mechanisms that do the explanatory work. William Bechtel emphasizes how mechanisms were discovered by cell biologists.
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Book details

List price: $31.99
Copyright year: 2008
Publisher: Cambridge University Press
Publication date: 4/28/2008
Binding: Paperback
Pages: 336
Size: 5.75" wide x 8.75" long x 0.75" tall
Weight: 0.990
Language: English

Introduction: Cell Mechanisms and Cell Biology
A different kind of science
The organization of science into disciplines
The new discipline of cell biology
Explaining Cellular Phenomena through Mechanisms
Historical conceptions of mechanism
Twentieth century conceptions of mechanism
Current conceptions of mechanisms
Representing and reasoning about mechanisms
Levels of organization and reduction
Organization: from Cartesian to biological mechanisms
Discovering and testing models of mechanisms
Conclusions
The Locus of Cell Mechanisms: Terra Incognita Between Cytology and Biochemistry
Cytological contributions to discovering cell mechanisms up to 1940
Biochemical contributions to discovering cell mechanisms up to 1940
The need to enter the Terra Incognita between cytology and biochemistry
Creating New Instruments and Research Techniques to Study Cell Mechanisms
The epistemology of evidence: judging artifacts
The ultracentrifuge and cell fractionation
The electron microscope and electron microscopy
A case study of an artifact charge
Equipped with new instruments and techniques to enter Terra Incognita
Entering the Terra Incognita Between Biochemistry and Cytology
First steps towards cell biology at the Rockefeller Institute: Claude's introduction of cell fractionation
Robert Bensley: an alternative approach to fractionalism
Competing interpretations of fractions from normal cells
Linking Claude's microsomes to protein synthesis
Adding a biochemical perspective to the Rockefeller Laboratory
Adding electron microscopy as a tool
The state of cell studies at the end of the 1940's
New Knowledge: the Mechanisms of the Cytoplasm
The mitochondrion
Microsomes, the endoplasmic reticulum, and ribosomes
Two additional organelles
Giving cell biology an institutional identity