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Biochemistry and Physiology of the Neutrophil

ISBN-10: 0521018501

ISBN-13: 9780521018500

Edition: 2005

Authors: Steven W. Edwards

List price: $88.00
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Description:

This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of this cell, highlighting the mechanisms by which they seek out and destroy pathogenic microorganisms. The development of these cells during haematopoiesis is described and the mechanisms that lead to the production of reactive oxidants and the intracellular signal transduction systems that lead to the cell's activation are reviewed. The book also discusses recent discoveries concerning the role of cytokines in the regulation of neutrophil function together with the importance of the neutrophil as a generator of inflammatory cytokines. Finally, there is a description of the biochemical defects that give rise to some of the neutrophil-associated human diseases.
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Book details

List price: $88.00
Copyright year: 2005
Publisher: Cambridge University Press
Publication date: 8/22/2005
Binding: Paperback
Pages: 320
Size: 6.00" wide x 9.00" long x 0.75" tall
Weight: 0.990
Language: English

Neutrophils and host defence: the fight against infection
The development and structure of neutrophils
The generation and recognition of neutrophil-activating factors: structure and function of neutrophil receptors
The cytoskeleton: the molecular framework regulating cell shape and the traffic of intracellular components
The respiratory burst: the generation of reactive oxygen metabolites and their role in microbial killing
Neutrophil activation: the production of intracellular signalling molecules
Neutrophil priming: regulation of neutrophil function during inflammatory activation
Disorders of neutrophil function
Index