ISBN-10: 047119350X

ISBN-13: 9780471193500

Edition: 3rd 2005 (Revised)

List price: $257.95
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Biochemistry 3rd edition DONALD VOET, University of Pennsylvania, USA and JUDITH G. VOET, Swarthmore College, USA Biochemistry is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge. * This edition has been updated to reflect the enormous advances in molecular and protein structure * Integrated Biochemical Interactions CD
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Book details

List price: $257.95
Edition: 3rd
Copyright year: 2005
Publisher: John Wiley & Sons, Incorporated
Publication date: 3/9/2004
Binding: Hardcover
Pages: 1616
Size: 9.00" wide x 11.25" long x 2.25" tall
Weight: 7.854
Language: English

Introduction and Background
Biochemistry: A Prologue
Genetics: A Review
The Origin of Life
The Biochemical Literature
Aqueous Solutions
Properties of Water
Acids, Bases, and Buffers
Thermodynamic Principles: A Review
First Law of Thermodynamics: Energy Is Conserved
Second Law of Thermodynamics: The Universe Tends toward Maximum Disorder
Free Energy: The Indicator of Spontaneity
Chemical Equilibria
Concentration Dependence of Free Energy
Amino Acids
The Amino Acids of Proteins
Optical Activity
"Nonstandard" Amino Acids
Nucleic Acids, Gene Expression, and Recombinant DNA Technology
Nucleotides and Nucleic Acids
DNA Is the Carrier of Genetic Information
Double Helical DNA
Gene Expression and Replication: An Overview
Molecular Cloning
Techniques of Protein and Nucleic Acid Purification
Protein Isolation
Solubilities of Proteins
Chromatographic Separations
Nucleic Acid Fractionation
Covalent Structures of Proteins and Nucleic Acids
Primary Structure Determination of Proteins
Nucleic Acid Sequencing
Chemical Evolution
Bioinformatics: An Introduction
Chemical Synthesis of Polypeptides
Chemical Synthesis of Oligonucleotides
Three-Dimensional Structures of Proteins
Secondary Structure
Fibrous Proteins
Globular Proteins
Protein Stability
Quaternary Structure
Viewing Stereo Pictures
Protein Folding, Dynamics, and Structural Evolution
Protein Folding: Theory and Experiment
Folding Accessory Proteins
Protein Structure Prediction and Design
Protein Dynamics
Conformational Diseases: Amyloids and Prions
Structural Evolution
Hemoglobin: Protein Function in Microcosm
Hemoglobin Function
Structure and Mechanism
Abnormal Hemoglobins
Allosteric Regulation
Derivation of Symmetry Model Equations
Sugars and Polysaccharides
Lipids and Membranes
Lipid Classification
Properties of Lipid Aggregates
Biological Membranes
Membrane Assembly and protein Targeting
Mechanisms of Enzyme Action
Introduction to Enzymes
Historical Perspective
Substrate Specificity
Regulation of Enzymatic Activity
A Primer of Enzyme Nomenclature
Rates of Enzymatic Reactions
Chemical Kinetics
Enzyme Kinetics
Effects of pH
Bisubstrate Reactions
Derivations of Michaelis-Menten Equation Variants
Enzymatic Catalysis
Catalytic Mechanisms
Serine Proteases
Drug Design
Introduction to Metabolism
Metabolic Pathways
Organic Reaction Mechanisms
Experimental Approaches to the Study of Metabolism
Thermodynamics of Phosphate Compounds
Oxidation-Reduction Reactions
Thermodynamics of Life
The Glycolytic Pathway
The Reactions of Glycolysis
Fermentation: The Anaerobic Fate of Pyruvate
Metabolic Regulation and Control
Metabolism of Hexoses Other than Glucose
Glycogen Metabolism
Glycogen Breakdown
Glycogen Synthesis
Control of Glycogen Metabolism
Glycogen Storage Diseases
Signal Transduction
Heterotrimeric G Proteins
Tyrosine Kinase-Based Signaling
The Phosphoinositide Cascade
Transport through Membranes
Thermodynamics of Transport
Kinetics and Mechanisms of Transport
ATP-Driven Active Transport
Ion Gradient-Driven Active Transport
Citric Acid Cycle
Cycle Overview
Metabolic Sources of Acetyl-Coenzyme A
Enzymes of the Citric Acid Cycle
Regulation of the Citric Acid Cycle
The Amphibolic Nature of the Citric Acid Cycle
Electron Transport and Oxidative Phosphorylation
The Mitochondrion
Electron Transport
Oxidative Phosphorylation
Control of ATP Production
Other Pathways of Carbohydrate Metabolism
The Glyoxylate Cycle
Biosynthesis of Oligosaccharides and Glycoproteins
The Pentose Phosphate Pathway
Light Reactions
Dark Reactions
Lipid Metabolism
Lipid Digestion, Absorption, and Transport
Fatty Acid Oxidation
Ketone Bodies
Fatty Acid Biosynthesis
Regulation of Fatty Acid Metabolism
Cholesterol Metabolism
Eicosanoid Metabolism: Prostaglandins, Prostacyclins, Thromboxanes, Leukotrienes, and Lipoxins
Phospholipid and Glycolipid Metabolism
Amino Acid Metabolism
Amino Acid Deamination
The Urea Cycle
Metabolic Breakdown of Individual Amino Acids
Amino Acids as Biosynthetic Precursors
Amino Acid Biosynthesis
Nitrogen Fixation
Energy Metabolism: Integration and Organ Specialization
Major Pathways and Strategies of Energy Metabolism: A Summary
Organ Specialization
Metabolic Homeostasis: Regulation of Appetite, Energy Expenditure, and Body Weight
Metabolic Adaptation
Nucleotide Metabolism
Synthesis of Purine Ribonucleotides
Synthesis of Pyrimidine Ribonucleotides
Formation of Deoxyribonucleotides
Nucleotide Degradation
Biosynthesis of Nucleotide Coenzymes
Expression and Transmission of Genetic Information
Nucleic Acid Structures
Double Helical Structures
Forces Stabilizing Nucleic Acid Structures
Supercoiled DNA
DNA Replication, Repair, and Recombination
DNA Replication: An Overview
Enzymes of Replication
Prokaryotic Replication
Eukaryotic Replication
Repair of DNA
Recombination and Mobile Genetic Elements
DNA Methylation and Trinucleotide Repeat Expansions
The Role of RNA in Protein Synthesis
RNA Polymerase
Control of Transcription in Prokaryotes
Posttranscriptional Processing
The Genetic Code
Transfer RNA and Its Aminoacylation
Ribosomes and Polypeptide Synthesis
Control of Eukaryotic Translation
Posttranslational Modification
Protein Degradation
Viruses: Paradigms for Cellular Function
Tobacco Mosaic Virus
Icosahedral Viruses
Bacteriophage [lambda]
Influenza Virus
Eukaryotic Gene Expression
Chromosome Structure
Genomic Organization
Control of Expression
Cell Differentiation and Growth
Molecular Physiology
Blood Clotting
Motility: Muscles, Cilia, and Flagella
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