Genomics, Proteomics and Vaccines

Name: Genomics, Proteomics and Vaccines
Availability: OutOfStock
ISBN: 9780470093924

ISBN-10: 0470093927

ISBN-13: 9780470093924

Edition: 2004

Authors: Guido Grandi

List price: $247.95

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Description:

While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput…

Book details

List price: $247.95
Copyright year: 2004
Publisher: John Wiley & Sons, Incorporated
Publication date: 8/13/2004
Pages: 352
Size: 6.97" wide x 9.92" long x 0.98" tall
Weight: 1.738



Preface


List of Contributors



Introduction



Vaccination: Past, Present and Future




Bioinformatics, DNA Microarrays and Proteomics in Vaccine Discovery: Competing or Complementary Technologies?




Technologies



Genome Sequencing and Analysis




Understanding DNA Microarrays: Sources and Magnitudes of Variances in DNA Microarray Data Sets




The proteome, Anno Domini Two Zero Zero Three




Mass Spectrometry in Proteomics




High Throughput Cloning, Expression and Purification Technologies




Applications



Meningococcus B: from Genome to Vaccine




Vaccines Against Pathogenic Streptococci




Identification of the 'Antigenome'-a Novel Tools for Design and Development of Subunit Vaccines Against Bacterial Pathogens




Searching the Chlamydia Genomes for New Vaccine Candidates




Proteomics and Anti-Chlamydia Vaccine Discovery




Proteome Analysis of Other Membrane and Extracelular Proteins from Pseudomonas aeruginosa for vaccine Discovery



Index