Hypospadias and Genital Development

Name: Hypospadias and Genital Development
Price: 99.15 USD
Availability: InStock
ISBN: 9780306481772

ISBN-10: 0306481774

ISBN-13: 9780306481772

Edition: 2004

Authors: Laurence S. Baskin

List price: $199.00

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Description:

This book focuses on the current basic science research of hypospadias and genital development. Congenital anomalies of the genitalia are the second most common birth abnormality besides congenital heart defects. Genital anomalies come in many varieties with the most common abnormality being hypospadias. The etiology of hypospadias remains unknown and the incidence is doubling in western countries with no definable explanation. It therefore seems especially germane to study this common congenital anomaly with a baseline incidence of 1/125-250 newborn males.

Book details

List price: $199.00
Copyright year: 2004
Publisher: Springer
Publication date: 3/31/2004
Binding: Hardcover
Pages: 400
Size: 6.50" wide x 9.75" long x 0.75" tall
Weight: 1.540
Language: English



Introduction


Human studies


Epidemiology of hypospadias


Endocrine evaluation of hypospadias


Endocrine abnormalities in boys with hypospadias


Genetic and clinical studies on hypospadias


Mechanism of genital development


Development of the penile urethra


Anatomical studies of the mouse genital tubercle


Anatomical studies of the fibroblast growth factor-10 mutant, sonic hedge hog mutant, and androgen receptor mutant mouse genital tubercle


Developmental genetics of hypospadias


Development of the mouse external genitalia : unique model of organogenesis


New concepts on the development of the vagina


Endocrine disruptors and sexual dimorphism in the animal kingdom


Endocrine disruption overview : are males at risk?


Endocrine disruption and hypospadias


Toxicant-induced hypospadias in the male rat


Masculinization of female mammals : lessons from nature


Index