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Cell Signalling

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ISBN-10: 0199232105

ISBN-13: 9780199232109

Edition: 3rd 2010

Authors: John Hancock

List price: $36.99
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Description:

Signalling within and between cells is an essential part of many biological processes, from the development of the body, to the activity of our immune system. Recent advances in molecular cell biology have allowed us to identify the components of signalling pathways, and examine how they interact to form the carefully orchestrated and controlled networks upon which the complexity of a living organism is built.Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms, before examining how these components come together to create signalling pathways, which are so crucial to the survival of many living organisms.Cell Signalling presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems.• A focus on generic components of extra- and intracellular signalling pathways allows the student to gain a thorough understanding of the underlying principles of cell signalling before exploring how the individual components inteeract to form complex signalling pathways• The ubiquity of key signalling mechanisms is highlighted, enabling students to see how similar mechanisms are conserved and harnessed in many different biological systems• The student is directed to carefully chosen further reading articles, allowing them to readily explore key topics in more detailOnline Resource CentreThe Online Resource Centre to accompany Cell Signalling features:For students:• Links to useful websites• Hyperlinked referencesFor Lecturers:• All figures from the book
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Book details

List price: $36.99
Edition: 3rd
Copyright year: 2010
Publisher: Oxford University Press
Publication date: 1/11/2017
Binding: Paperback
Pages: 352
Size: 9.60" wide x 7.40" long x 0.70" tall
Weight: 1.914
Language: English

John Hancock spent over 20 years in financial services working for Sun Life, Mondial Citibank and Hill Samuel. Since the early 1990s he has worked as an established freelance financial journalist writing for Money Management, the Financial Times, The Times and Director magazine. He also writes for corporate clients and Web sites and edits Selling Financial Services, the leading publication for independent financial advisors. John is a member of Mensa and was Ethical Investment Journalist of the Year 1999.

Figure Legends
Preface
Abbreviations
An overview of cell signalling
Aspects of cellular signalling
Pathways are the key to signalling
A look at some of the history and techniques of cell signalling
Components which comprise signalling pathways
Extracellular signals: hormones, cytokines and growth factors
Detection of extracellular signals: the role of receptors
Protein Phosphorylation, kinases and phosphatases
Cyclic nucleotides, cyclases and G proteins
Inositol phosphate metabolism and roles of membrane lipids
Intracellular calcium: Its control and role as an intracellular signal
Reactive oxygen species, reactive nitrogen species and redox signalling
Selected examples of signalling pathways and events
Insulin and the signal transduction cascades it invokes
Perception of the environment
Signalling in development and for the regulation of gene expression
Life, death and apoptosis
Final thoughts
Cell Signalling: importance, complexity, and future
Index