Glial Cell Development Basic Principles and Clinical Relevance

Name: Glial Cell Development Basic Principles and Clinical Relevance
Availability: OutOfStock
ISBN: 9780198524786

ISBN-10: 0198524781

ISBN-13: 9780198524786

Edition: 2nd 2001 (Revised)

Authors: Kristjan R. Jessen, William D. Richardson, William D. Richardson

List price: $315.00

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This is a new edition in the Cellular and Molecular Neurobiology series. The majority of cells in the nervous system are glial cells. During development, these cells provide growth factors that stimulate the proliferation, migration and survival of neurones and their precursors, and promote and guide axonal growth. In the mature nervous system, glial cells provide insulating myelin sheath around axons and provide metabolic and structural support for neurones. Glial cells also have a major influence on the local response to injury of central nerve tracts and the peripheral nervous system, either promoting, or inhibiting, axonal regrowth and recovery of lost function. This book provides a…

Book details

List price: $315.00
Edition: 2nd
Copyright year: 2001
Publisher: Oxford University Press, Incorporated
Publication date: 11/29/2001
Binding: Hardcover
Pages: 488
Size: 6.50" wide x 9.75" long x 1.25" tall
Weight: 2.398
Language: English




Embryonic and early postnatal development of Schwann cells




Origins and early development of oligodendrocytes




Developmental origins of astrocytes




Microglia in the developing and mature central nervous system




The metabolic functions of glial cells during development & in maturity




The role of ion channels and transmitter receptors on glial cells




Structure and formation of the node of Ranvier




Myelin sheath structure, function and evolution




Myelin-specific genes and their mutations in the mouse




Control of gene expression by oligodendrocytes




Transcription factors that control Schwann cell development and myelination




Genetic analysis of gliogenesis in Drosophila




Functions of astrocytes




Glial influences on axonal growth




Axon-Schwann cell interactions during peripheral nerve degeneration & regeneration




The molecular genetics of hereditary demyelinating neuropathies




Genetic & cellular mechanisms of Schwann cell tumour formation: neurofibromatosis type 1 and neurofibromatosis type 2




The neuropathology of Multiple Sclerosis




Restoring CNS myelin by glial cell transplantation, Blakemore




Stem cells and their gliogenic potential




Glial tumours of the CNS