Skip to content

Cancer Biology

Spend $50 to get a free movie!

ISBN-10: 0131294547

ISBN-13: 9780131294547

Edition: 3rd 2006 (Revised)

Authors: Roger J. B. King, Mike W. Robins

List price: $125.60
Blue ribbon 30 day, 100% satisfaction guarantee!
Out of stock
what's this?
Rush Rewards U
Members Receive:
Carrot Coin icon
XP icon
You have reached 400 XP and carrot coins. That is the daily max!

Provides a clear, concise and authoritative introduction to the biological principles that underlie the causes and treatment of cancer. The authors draw on their extensive teaching experience to guide students through this complex subject, and knit together the diverse areas encompassed in the study of cancer. This third edition is updated to include areas of recent research which excite student interest.
Customers also bought

Book details

List price: $125.60
Edition: 3rd
Copyright year: 2006
Publisher: Benjamin-Cummings Publishing Company
Publication date: 5/24/2006
Binding: Paperback
Pages: 312
Size: 7.25" wide x 9.75" long x 0.75" tall
Weight: 1.584
Language: English

Detailed contents
Preface to the second edition
Preface to the first edition
Basic science, terminology and abbreviations
What is cancer?
Carcinogenesis requires several cellular changes
Lifestyle and family influences on cancer
Changes continue to accumulate after cancer formation
Cancers are most common in epithelial cells
Cancer results from uncontrolled growth
Cancer genesInvasion and metastasis
Some cancers are curable
Prevention, screening and treatment
Further reading
Natural history: the life of a cancer
Clonal origins of cancer
Experimental biology
Box 2.1: Special mice used in cancer research
Clinical dataLinking laboratory and clinic
Pathology: defining a neoplasm
Box 3.1: Classifying cancers
Molecular techniques
Further reading
Epidemiology: identifying causes for human cancers
Descriptive epidemiology
Box 4.1: Epidemiological methods and terminology
Analytical epidemiology
Criteria required to establish causality
Molecular epidemiology
Factors that influence human carcinogenesis
Cancer prevention
Further reading
Oncogenes, tumour suppressor genes and viruses
Box 5.1: Molecular terms relevant to genes and their regulation
Tumour suppressor genes
Oncogenes and tumour suppressors cooperate
Further reading
Chemical and radiation carcinogenesis
Chemical carcinogenesis
Radiation carcinogenesis
Consequences of DNA damage
Predicting the type of carcinogen by mutational spectrum analysis
Further reading
Mutations, DNA repair and genetic instability
Genetic instability
Types of DNA damage
Clinical evidence that links DNA repair and carcinogenesis
Repair mechanisms
Coordination of DNA repair, proliferation and apoptosis
Further reading
Familial cancers
Box 8.1: Chromosome nomenclature and structure
Strong familial link
Weaker familial link
Connection with sporadic cancers
Further reading
Growth: a balance of cell proliferation, death and differentiation
Normal proliferation and its regulation
Box 9.1: BNA synthesis and telomere length
Cancer cells
Senescence, cell mortality and telomerase
Cell death
Apoptosis and cancer
Integration of proliferation, apoptosis and DNA repair
Further reading
Responding to the environment: growth regulation and signal transduction
General features
Growth factors
Growth factor receptors
Growth factors: from membrane to nucleus
Nuclear events stimulated by growth factors
Cell adhesion molecules
Box 10.1: How a cell interacts with its environment
Hydrophobic growth regulatory molecules
Cross-talk between signalling pathways
Further reading
Invasion and metastasis
General features
Escape from local control and invasion
Gene changes involved in metastasis
Further reading
Principles of cancer treatment
Principles behind the treatment of cancer
Hormone therapy
Immunotherapy/biological response modifier therapy
Photodynamic therapy
New forms of treatment
Further reading
Approaches to cancer prevention
Breast cancer, tamoxifen and anastrozole
Endometrial/ovarian cancer and the contraceptive pill
Coloncancer and non-steroidal anti-inflammatory drugs
Further reading
Features of selected cancers