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| Preface | |
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| About the Authors | |
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| Introduction | |
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| The Human Genome and Beyond | |
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| Transcription and Translation | |
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| Ion Channels | |
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| The First Law: Energy Is Conserved | |
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| Energy Conversion and Conservation | |
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| Describing the State of a System | |
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| Phase Changes | |
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| Chemical Reactions | |
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| Molecular Interpretations of Energy and Enthalpy | |
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| Mathematics Needed for Chapter 2 | |
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| The Second Law: The Entropy of the Universe Increases | |
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| Historical Development of the Second Law: The Carnot Cycle | |
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| A New State Function, Entropy | |
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| The Second Law of Thermodynamics: Entropy Is Not Conserved | |
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| Molecular Interpretation of Entropy | |
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| Measurement of Entropy | |
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| Chemical Reactions | |
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| Third Law of Thermodynamics | |
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| Gibbs Free Energy | |
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| Helmholtz Free Energy | |
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| Noncovalent Reactions | |
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| Use of Partial Derivatives in Thermodynamics | |
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| Free Energy and Chemical Equilibria | |
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| Chemical Potential (Partial Molar Gibbs Free Energy) | |
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| Reactions of Gases: The Ideal Gas Approximation | |
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| Nonideal Systems | |
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| The Equilibrium Constant and the Standard Gibbs Free Energies of the Reactants and Products | |
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| Galvanic Cells | |
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| Biochemical Applications of Thermodynamics | |
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| Mathematics Needed for Chapter 4 | |
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| Free Energy and Physical Equilibria | |
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| Phase Equilibria | |
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| Membranes | |
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| Active and Passive Transport | |
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| Colligative Properties | |
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| Molecular-Weight Determination | |
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| Internet | |
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| Molecular Motion and Transport Properties | |
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| Kinetic Theory | |
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| Molecular Collisions | |
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| Mean Free Path | |
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| Diffusion | |
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| Sedimentation | |
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| Determination of Molecular Weights from Sedimentation and Diffusion | |
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| Viscosity | |
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| Electrophoresis | |
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| Size and Shape of Macromolecules | |
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| Kinetics: Rates of Chemical Reactions | |
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| Kinetics | |
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| Reaction Mechanisms and Rate Laws | |
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| Temperature Dependence | |
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| Transition-State Theory | |
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| Electron Transfer Reactions: Marcus Theory | |
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| Ionic Reactions and Salt Effects | |
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| Isotopes and Stereochemical Properties | |
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| Very Fast Reactions | |
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| Diffusion-Controlled Reactions | |
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| Photochemistry and Photobiology | |
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| Photosynthesis | |
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| Mathematics Needed for Chapter 7 | |
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| Enzyme Kinetics | |
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| Enzyme Kinetics | |
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| Michaelis-Menten Kinetics | |
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| Competition and Inhibition | |
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| Mathematics Needed for Chapter 8 | |
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| Molecular Structures and Interactions: Theory | |
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| The Process of Vision | |
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| Origins of Quantum Theory | |
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| Quantum Mechanical Calculations | |
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| Schrodinger's Equation | |
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| Particle in a Box | |
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| Tunneling | |
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| Simple Harmonic Oscillator | |
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| Rigid Rotator | |
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| Hydrogen Atom | |
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| Electron Distribution | |
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| Molecular Structure and Molecular Orbitals | |
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| Intermolecular and Intramolecular Forces | |
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| Noncovalent Interactions | |
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| Molecular Dynamics Simulation | |
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| Outlook | |
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| Schrodinger's Equation | |
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| Some Useful Operators | |
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| Mathematics Needed for Chapter 9 | |
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| Molecular Structures and Interactions: Spectroscopy | |
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| Electromagnetic Spectrum | |
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| Color and Refractive Index | |
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| Absorption and Emission of Radiation | |
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| Proteins and Nucleic Acids: Ultraviolet Absorption Spectra | |
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| Fluorescence | |
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| Optical Rotatory Dispersion and Circular Dichroism | |
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| Circular Dichroism of Nucleic Acids and Proteins | |
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| Vibrational Spectra, Infrared Absorption, and Raman Scattering | |
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| Nuclear Magnetic Resonance | |
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| Interactions in Nuclear Magnetic Resonance | |
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| Molecular Distributions and Statistical Thermodynamics | |
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| Binding of Small Molecules by a Polymer | |
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| The Random Walk | |
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| Helix-Coil Transitions | |
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| Statistical Thermodynamics | |
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| Mathematics Needed for Chapter 11 | |
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| Macromolecular Structure and X-Ray Diffraction | |
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| Visible Images | |
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| X Rays | |
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| Determination of Molecular Structure | |
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| Electron Diffraction | |
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| Neutron Diffraction | |
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| Electron Microscopy | |
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| Mathematics Needed for Chapter 12 | |
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| Appendix | |
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| Answers | |
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| Index | |