| |
| |
| Foreword: A Brief and Highly Selective History of Ideas About Platelets in Health and Disease | |
| |
| |
| Biology The Evolution of Mammalian Platelets | |
| |
| |
| Megakaryocyte Development and Platelet Formation | |
| |
| |
| Platelet Structure | |
| |
| |
| Platelet Turnover and Aging | |
| |
| |
| Platelet Receptors | |
| |
| |
| The GPIb-IX-V Complex | |
| |
| |
| Integrin aIIbb3 | |
| |
| |
| Thrombin Receptors | |
| |
| |
| P-Selectin/PSGL-1 and Other Interactions Between Platelets, Leukocytes, and Endothelium | |
| |
| |
| Platelet Polymorphisms | |
| |
| |
| Platelet Secretion | |
| |
| |
| Signal Transduction During the Initiation, Extension, and Perpetuation of Platelet Plug Formation | |
| |
| |
| Platelet Thrombus Formation in Flowing Blood | |
| |
| |
| Interactions Between Platelets and the Coagulation System | |
| |
| |
| Platelet-Derived Microparticles | |
| |
| |
| Platelet Function in the Newborn | |
| |
| |
| Tests of Platelet Function Platelet Count | |
| |
| |
| The Bleeding Time | |
| |
| |
| Platelet Aggregation | |
| |
| |
| Flow Cytometry | |
| |
| |
| Ultegra Rapid Platelet Function Analyzer | |
| |
| |
| Platelet Function Analyzer (PFA)-100 | |
| |
| |
| Cone and Plate(let) Analyzer | |
| |
| |
| Perfusion Chambers | |
| |
| |
| Animal Models | |
| |
| |
| The Role of Platelets in Disease Atherosclerosis and Coronary Artery Disease | |
| |
| |
| Ischemic Cerebrovascular Disease | |
| |
| |
| Peripheral Vascular Disease | |
| |
| |
| Diabetes Mellitus | |
| |
| |
| Renal Disease | |
| |
| |
| Inflammation | |
| |
| |
| Antimicrobial Host Defense | |
| |
| |
| Tumor Growth and Metastasis | |
| |
| |
| Alzheimer Disease | |
| |
| |
| Psychiatric Disorders | |
| |
| |
| Disorders of Platelet Number and Function The Clinical Approach to Disorders of Platelet Number and Function | |
| |
| |
| Immune Thrombocytopenic Purpura | |
| |
| |
| HIV-1-related Thrombocytopenia | |
| |
| |
| Heparin-induced Thrombocytopenia | |
| |
| |
| Drug-induced Thrombocytopenia | |
| |
| |
| Thrombotic Thrombocytopenic Purpura and Hemolytic-Uremic Syndrome | |
| |
| |
| Thrombocytopenia in Pregnancy | |
| |
| |
| Thrombocytopenia in the Newborn | |
| |
| |
| Pseudothrombocytopenia | |
| |
| |
| Thrombocytosis and Essential Thrombocythemia | |
| |
| |
| Inherited Disorders of Platelet Function | |
| |
| |
| Acquired Disorders of Platelet Function | |
| |
| |
| Cardiopulmonary Bypass | |
| |
| |
| Pharmacology: Antiplatelet Therapy Aspirin | |
| |
| |
| GPIIb-IIIa Antagonists | |
| |
| |
| Clopidogrel and Ticlopidine | |
| |
| |
| Dipyridamole | |
| |
| |
| Cilostazol | |
| |
| |
| Pharmacology: Therapy to Increase Platelet Numbers and/or Function Thrombopoietin | |
| |
| |
| Interleukin | |
| |
| |
| Desmopressin | |
| |
| |
| Factor VIIa | |
| |
| |
| Transfusion Medicine Platelet Storage and Transfusion | |
| |
| |
| Platelet Transfusion in Infants and Children | |
| |
| |
| Platelet Substitutes and Novel Methods of Platelet Preservation | |
| |
| |
| Gene Therapy Gene Therapy for Platelet Disorders | |