| |
| |
| Dynamic GFP Sensors for High-Content Analysis of the Cell Cycle | |
| |
| |
| High Content Fluorescence-based Screening for Epigenetic Modulators | |
| |
| |
| Development of Assays for Nuclear Receptor Modulators Using Fluorescently Tagged Proteins | |
| |
| |
| The Ligand-Independent Translocation Assay: An Enabling Technology for Screening Orphan GPCRs by Arrestin Recruitment | |
| |
| |
| High Content Screening of Known G Protein-Coupled Receptors by Arrestin Translocation | |
| |
| |
| Cell Imaging Assays for G protein-coupled Receptor Internalization: Application to High Throughput Screening | |
| |
| |
| High throughput confocal microscopy for beta arrestin-GFP translocation GPCR assays using the Evotec Opera | |
| |
| |
| G-protein coupled receptor internalization assays in the High Content Screening Format | |
| |
| |
| Screening for Activators of the Wnt/Fzd Pathway by Automated Fluorescent Microscopy | |
| |
| |
| A live-cell, image based approach to understanding the enzymology and pharmacology of 2-bromopalmitate and palmitoylation | |
| |
| |
| Quantitative single cell studies of nuclear receptor function using high-resolution HTM and image analyses | |
| |
| |
| Tracking the motion of individual proteins with semiconductor quantum dots | |
| |
| |
| Development and Application of Automatic High Resolution Light Microscopy for Cell Based Screens | |
| |
| |
| Adenoviral Sensors for High-Content Cellular Analysis | |
| |
| |
| Cell based assays in primary endothelial cells to study multiple steps in inflammation | |
| |
| |
| Development and Implementation of Multiplexed Cell-Based Imaging Assays | |
| |
| |
| High throughput screening for modulators of stem cell differentiation | |
| |
| |
| High Content Kinetic Calcium Imaging in Drug Sensitive and Drug Resistant Human Breast Cancer Cells | |
| |
| |
| Measurement and Analysis of Calcium Signaling in Heterogeneous Cell Cultures | |
| |
| |
| Mulipliex Analysis of Inflammatory Signalling Pathways using a High Content Imaging System | |
| |
| |
| Generation and Characterization of a Stable MK2-EGFP Cell Line and Subswquent Development of a High Content Imaging Assay on the Cellomics ArrayScan“ Platform to Screen for p38 MAPK Inhibitors | |
| |
| |
| Development and implementation of three MAPK signaling pathway imaging assays to provide MAPK module selectivity profiling for kinase inhibitors; MK2-EGFP translocation, c-Jun & ERK activation | |
| |
| |
| Assay Development and Case History of a 32K Biased Library High Content MK2-EGFP Translocation Screen to Identify p38 MAPK Inhibitors on the ArrayScan“ 3.1 Imaging Platform | |
| |
| |
| Development and Implementation of a dual target MAPK high content assay (MK2-EGFP translocation & cJun activation) to provide LO support for kinase inhibitors | |
| |
| |
| Compound classification using image-based cellular phenotypes | |
| |
| |
| High Content Screening: Emerging Hardware and Software Technologies | |
| |
| |
| An Infrastructure for High Throughput Microscopy: Instrumentation, Informatics, and Integration | |
| |
| |
| Protein Translocation Assays: Key Tools for Accessing New Biological Information with High Throughput Microscopy | |
| |
| |
| High-Content Screening of Functional Genomic Libraries | |
| |
| |
| Fluorescent protein-based cellular assays analyzed by laser scanning microplate cytometry in 1536-well plate format | |
| |
| |
| High-Throughput Measurements of Biochemical Responses Using the Plate::VisionT Multimode 96 Mini-lens Array Reader | |
| |
| |
| Systems Cell Biology Based on High Content Screening | |
| |
| |
| Digital Autofocus Methods for Automated Microscopy | |
| |
| |
| Fluorescence Lifetime Imagine Microscopy - Two-dimensional distribution measurement of fluorescence lifetime | |