Forensic DNA Typing Biology, Technology, and Genetics of STR Markers

ISBN-10: 0121479528

ISBN-13: 9780121479527

Edition: 2nd 2005 (Revised)

Authors: John M. Butler

List price: $96.95
eBook available
30 day, 100% satisfaction guarantee

If an item you ordered from TextbookRush does not meet your expectations due to an error on our part, simply fill out a return request and then return it by mail within 30 days of ordering it for a full refund of item cost.

Learn more about our returns policy


Since the enormously successful first edition of Forensic DNA Typing was published, the Human Genome Project has published a draft sequence of the human genome and completed the finished reference sequence. The advent of modern DNA technology has resulted in the increased ability to perform human identity testingdesirable in a number of situations including the determination of perpetrators of violent crime such as murder and rape, resolving unestablished paternity, and identifying remains of missing persons or victims of mass disasters. The technology has been utilized in identifying remains from victims of the World Trade Center twin towers collapse following the terrorist attacks of September 11, 2001, the President Clinton-Monica Lewinsky scandal, and the identification of the remains in the Tomb of the Unknown Soldier. Indeed, our perceptions of history have been changed with DNA evidence that revealed Thomas Jefferson fathered a child by one of his slaves. This book examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century.
eBooks Starting from $94.95
Buy eBooks
what's this?
Rush Rewards U
Members Receive:
You have reached 400 XP and carrot coins. That is the daily max!
Study Briefs

Limited time offer: Get the first one free! (?)

All the information you need in one place! Each Study Brief is a summary of one specific subject; facts, figures, and explanations to help you learn faster.

Add to cart
Study Briefs
Italian Grammar Online content $4.95 $1.99
Add to cart
Study Briefs
Portuguese Grammar Online content $4.95 $1.99
Add to cart
Study Briefs
Spanish Grammar Online content $4.95 $1.99
Customers also bought

Book details

List price: $96.95
Edition: 2nd
Copyright year: 2005
Publisher: Elsevier Science & Technology Books
Publication date: 2/22/2005
Binding: Hardcover
Pages: 688
Size: 8.00" wide x 10.25" long x 2.00" tall
Weight: 4.4
Language: English

John M. Butler is a NIST Fellow and Group Leader at the U.S. National Institute of Standards and Technology, Gaithersburg, Maryland. Dr. Butler earned his PhD from the University of Virginia while doing DNA research in the FBI Laboratory's Forensic Science Research Unit. He has over 100 publications in this field and is a frequent presenter on the topic of DNA typing.

Overview and history of DNA typing
DNA biology review
Sample collection, DNA extraction and DNA quantitation
The polymerase chain reaction (DNA amplification)
Commonly used short tandem repeat markers and commercial kits
Biology of STRs : stutter products, non-template addition, microvariants, null alleles and mutation rates
Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number
Single nucleotide polymorphisms and other bi-allelic markers
Y chromosome DNA testing
Mitochondrial DNA analysis
Non-human DNA testing and microbial forensics
DNA separation methods : slab gel and capillary electrophoresis
DNA detection methods : fluorescent dyes and silver-staining
Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems
STR genotyping issues
Laboratory validation
New technologies, automation, and expert systems
Combined DNA index system (CODIS) and the use of DNA databases
Basic genetic principles, statistics, and probability
STR population database analyses
Profile frequency estimates, likelihood ratios, and source attribution
Approaches to statistical analysis of mixtures and degraded DNA
Kinship and parentage testing
Mass disaster DNA victim identification
Reported STR alleles : sizes and sequences
U.S. population data - STR allele frequencies
Suppliers of DNA analysis equipment, products, OR services
DNA advisory board quality assurance standards
DAB recommendations on statistics
NRC II recommendations
Example DNA cases
Free shipping on orders over $35*

*A minimum purchase of $35 is required. Shipping is provided via FedEx SmartPost® and FedEx Express Saver®. Average delivery time is 1 – 5 business days, but is not guaranteed in that timeframe. Also allow 1 - 2 days for processing. Free shipping is eligible only in the continental United States and excludes Hawaii, Alaska and Puerto Rico. FedEx service marks used by permission."Marketplace" orders are not eligible for free or discounted shipping.

Learn more about the TextbookRush Marketplace.