Immunoglobulin Genes

Name: Immunoglobulin Genes
Availability: OutOfStock
ISBN: 9780120536405

ISBN-10: 0120536404

ISBN-13: 9780120536405

Edition: 2nd 1995

Authors: Tasuku Honjo, Frederick W. Alt

List price: $59.95

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Description:

The immunoglobulin gene complex is responsible for generating an extraordinarily wide range of antibodies, each possessing a unique antigen specificity. The Second Edition of Immunoglobulin Genes brings the reader up to date with the rapid progress in our understanding of this system. Firmly established as the definitive book on the topic, it provides a fully comprehensive account of the organization, function, rearrangement and expression of these and related genes. Since the publication of the first edition, the work has been extensively revised and updated to cover new research data on human immunoglobulin genes as well as mammalian and lower vertebrate systems. New chapters include…

Book details

List price: $59.95
Edition: 2nd
Copyright year: 1995
Publisher: Elsevier Science & Technology Books
Publication date: 10/12/1995
Binding: Hardcover
Pages: 443
Size: 6.12" wide x 9.25" long x 1.11" tall
Weight: 1.540
Language: English



B Cells: Human B-Cell Differentiation


Murine B-Cell Differentiation


Somatic Mutation and B-Cell Maturation


Development of B-Cell Subsets


Regulation of B-Cell Differentiation By Stroma Cells


Antigen Receptors


Organization and Rearrangement of Immunoglobulin Genes: Immunoglobulin Heavy Chain Loci in Mouse and Men


The Human Immunoglobulin Genes


Organization of Lambda Chain Genes


VDJ Recombination


Regulation of Class Switch Recombination of the Immunoglobulin Heavy Chain Genes


Organization and Expression of Chicken and Sheep Ig Genes


Immunoglobulin Heavy Chain Genes of Rabbit


The Structure and Organization of Immunoglobulin Genes in Lower Vertebrates


Immunoglobulin Gene Expression: Ig Gene Expression and Regulation in Ig Transgenic Mice


B-Lymphocyte Tolerance in the Mouse


Auto Antibodies


Regulation of Ig H and L Chain Gene Transcription


Subject Index