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Comprehensive Toxicology, Volume 5 Toxicology of the Immune System

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ISBN-10: 008042970X

ISBN-13: 9780080429700

Edition: 1997

Authors: D. A. Lawrence

List price: $260.00
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Description:

Volume 5 provides current knowledge regarding the intricacies of the immune system and the manner by which environmental agents can disrupt immune homeostasis and induce pathologies. The volume begins with an introduction to the field of immunotoxicology and an overview of the immune system. This is followed by a description of the cellular components of the immune system and how their development and reactivities can be modified. The architecture of the immune system is described as well as immunology, e.g. pulmonary and mucosal immunology. Immune functions specifically delineated include cell trafficking, processing of antigens, the manner by which cells communicate and are signaled into…    
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Book details

List price: $260.00
Copyright year: 1997
Publisher: Elsevier Science & Technology
Publication date: 8/4/1999
Binding: Hardcover
Pages: 534
Size: 7.50" wide x 10.75" long x 1.25" tall
Weight: 3.234
Language: English

Immunotoxicology: the merger of immunology and toxicology
Overview of the immune system
T-cell development
B-cell development
Natural killer cells
Phagocytes
Lymphoid tissue architecture and pathological influences of toxicants
Pulmonary immunology
Mucosal immunology
Skin immunology
Neuroimmunology
The immunology of pregnancy
Leukocyte trafficking
Antigen processing and presentation
Lymphocyte Antigen Receptor and Coreceptor Regulation of Tyrosine Kinases and Phosphatases: Effects of Oxidative Stress on Receptor Functions
Signal transduction pathways in B lymphocytes
T cell regulatory functions
The regulation of B cell activation through cogante interactions with T helper cells and the actions of T cell-dervied soluble mediators
Regulation of transcription by immunotoxicants
Antibody-mediated hypersensitivity
Chemically induced allergy and autoimmunity: what do T cells react against?
Hypersensitivity reactions in the lung
Contact hypersensitivity
Autoimmune models
Environmental and drug-induced autoimmune diseases of humans
Aging and the immune system
Immunotoxicology of cancer and prospects for its correction
Immunosuppressive drug and toxicant effects on transplant recipients
Immunotoxicology of recombinant DNA-derived Therapeutic proteins
Cytotoxic T cells
Stress and immune function
Immunomodulation by toxicant-induced stress proteins
Immunotoxicological methods and applications: animal models