Cancer Chemotherapy and Biotherapy Principles and Practice

ISBN-10: 1605474312

ISBN-13: 9781605474311

Edition: 5th 2011 (Revised)

List price: $184.00
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Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. The previous edition was one of "Doody's Core Titles 2009." This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised.
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Book details

List price: $184.00
Edition: 5th
Copyright year: 2011
Publisher: Lippincott Williams & Wilkins
Publication date: 12/1/2010
Binding: Hardcover
Pages: 848
Size: 8.37" wide x 10.87" long x 1.50" tall
Weight: 4.884
Language: English

Dan L. Longo, MDScientific DirectorNational Institute on AgingNational Institutes of HealthBethesda, Maryland

Basic Principles Of Cancer Treatment
Clinical Strategies for Cancer Treatment: The Role of Drugs
Target Identification and Drug Discovery
Clinical Drug Development and Approval for Marketing
Principles of Pharmacokinetics
Special Aspects of Brain Tumor Chemotherapy
Barriers to Drug Delivery
Cytotoxic Agents
Cytidine Analogues
Purine Analogues
Antimitotic Drugs
Alkylating Agents (Including Methylating Agents)
Platinum Analogues
Antitumor Antibiotics (Including Bleomycin)
Topoisomerase I Inhibitors
Topoisomerase II Inhibitors: Anthracyclines
Topoisomerase II Inhibitors: Etoposide, Teniposide
Molecularly Targeted Therapies
Proteosome Inhibitors
HDAC Inhibitors
Differentiating Agents (Retinoids)
Arsenic Trioxide
Monoclonal Antibodies: Discovery & Development
Anti-angiogenic Agents (Including MonAB)
Anti-EGFR Therapies (Including MonAB)
Anti-her 2 Therapies
Intracellular Signal Inhibitors (bcr-abl)
Signal Transduction Inhibitors in Development
Inhibitors of the PI3k Pathway & Mitotic Kinase
Immunologic Agents
Interferon and Cytokines
Adoptive Cellular Therapies
Immuno-modulatory Drugs (IMIDS, Anti-CTLA4)
Hormonal Therapy
Hormonal Therapy of Breast Cancer
GNRH Agonists and Anti-Androgens
Supportive Care
Pain Management in Cancer Patients
Colony Stimulating Factors
Anti-nausea Medications
Bone Loss Modulators
Intravenous Access and Catheter Management
Monitoring for Late Side Effects of Chemotherapy
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