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| Third edition editorial board | |
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| Contributors | |
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| Acknowledgements | |
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| Preface | |
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| Introduction | |
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| Overview | |
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| Organisation of information in the Guide | |
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| Sources of information and disclaimer | |
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| UCLH policies | |
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| Responsibilities of professional staff at UCLH | |
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| Preparation of injectable medicines on wards, clinics and departments at UCLH | |
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| An overview of intravenous therapy | |
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| When is intravenous therapy appropriate? | |
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| Drug factors that influence the choice of route | |
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| Disadvantages of intravenous administration | |
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| Route of intravenous administration | |
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| Factors affecting patency of IV sites | |
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| Factors increasing failure of IV sites | |
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| Factors decreasing failure of IV sites | |
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| Occlusion of central venous catheters | |
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| Methods of intravenous administration | |
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| Intravenous bolus | |
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| Intermittent intravenous infusion | |
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| Continuous intravenous infusion | |
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| Preparation and administration of intravenous medicines | |
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| Aseptic non-touch technique (ANTT) | |
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| Extravasation of injectables: overview and management advice | |
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| Patient factors affecting extravasation | |
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| Medicine factors affecting extravasation | |
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| Administration factors affecting extravasation | |
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| Overall risk for extravasation | |
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| Treatment of extravasation | |
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| Flushing cannulae, catheters and administration sets | |
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| Flushing between medicines | |
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| When not to flush | |
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| Flushing catheters and cannulae not in use | |
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| Flushing with heparin | |
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| Infusion pumps | |
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| Pumps used at UCLH | |
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| Volumetric pumps | |
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| Syringe pumps | |
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| Pumps for ambulatory use | |
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| Patient-controlled analgesia (PCA) pumps | |
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| Target-controlled anaesthesia (TCI or TIVA) pumps | |
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| Administration of injectables in primary care | |
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| Self-caring patients | |
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| Formulation and presentation of injectables | |
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| Medicines that require reconstitution | |
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| Preparations in solution requiring further dilution before use | |
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| Preparations available 'ready to use' without further dilution | |
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| Preparations available 'ready to use' | |
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| Pharmaceutical aspects of injectable administration | |
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| Displacement values | |
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| Sodium content | |
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| Drop size | |
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| Layering | |
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| Fluid restriction | |
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| Factors influencing medicine stability and compatibility of injectable medicines | |
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| Degradation | |
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| Precipitation | |
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| Binding of medicines to plastics | |
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| Destabilisation of parenteral emulsions | |
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| Leaching of plasticisers | |
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| Blood and blood products | |
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| Allergic reactions to injectables | |
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| Latex allergy | |
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| Compatibility of drugs in a syringe driver for subcutaneous use | |
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| Risk assessment of injectables and risk reduction | |
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| Risk assessment | |
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| Risk reduction | |
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| Useful resources | |
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| Websites | |
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| Further reading | |
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| User Guide | |
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| Monographs in alphabetical order | |
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| Index | |