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| Preface | |
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| Acknowledgements | |
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| Note on the tenth edition | |
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| How to use this book | |
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| Further reading | |
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| List of abbreviations | |
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| Immunity | |
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| The scope of immunology | |
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| Innate and adaptive immune mechanisms | |
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| Recognition and receptors: the keys to immunity | |
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| Cells involved in immunity: the haemopoietic system | |
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| Innate immunity | |
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| Receptors of the innate immune system | |
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| Complement | |
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| Acute infl ammation | |
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| Phagocytic cells and the reticuloendothelial system | |
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| Phagocytosis | |
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| Adaptive immunity | |
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| The molecular basis | |
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| Evolution of recognition molecules: the immunoglobulin superfamily | |
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| The major histocompatibility complex | |
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| The T-cell receptor | |
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| Antibody diversifi cation and synthesis | |
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| Antibody structure and function | |
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| The cellular basis | |
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| Lymphocytes | |
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| Primary lymphoid organs and lymphopoiesis | |
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| Secondary lymphoid organs and lymphocyte traffic | |
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| The adaptive immune response | |
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| Antigen processing and presentation | |
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| The antibody response | |
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| Antigen - antibody interaction and immune complexes | |
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| Cell-mediated immune responses | |
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| Regulation | |
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| Tolerance | |
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| Cell communication and cytokines | |
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| The cytokine network | |
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| Immunity, hormones and the brain | |
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| Potentially useful immunity | |
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| Antimicrobial immunity: a general scheme | |
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| Immunity to viruses | |
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| HIV and AIDS | |
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| Immunity to bacteria | |
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| Immunity to fungi and ectoparasites | |
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| Immunity to protozoa | |
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| Immunity to worms | |
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| Undesirable effects of immunity | |
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| Immunodeficiency | |
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| Harmful immunity: a general scheme | |
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| Allergy and anaphylaxis | |
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| Immune complexes, complement and disease | |
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| Chronic and cell-mediated infl ammation | |
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| Autoimmune disease | |
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| Altered immunity | |
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| Transplant rejection | |
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| Immunosuppression | |
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| Immunostimulation and vaccination | |
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| Immunity in health and disease | |
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| Cancer immunology | |
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| Immunity and clinical medicine | |
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| Investigating immunity | |
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| Immunology in the laboratory | |
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| Out of the past: evolution of immune mechanisms | |
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| Into the future: immunology in the age of genomics | |
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| Self-assessment | |
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| Self-assessment questions | |
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| Answers | |
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| Appendices | |
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| Comparative sizes and molecular weights | |
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| Landmarks in the history of immunology and some unsolved problems | |
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| CD classification | |
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| Index | |