| |
| |
| |
Observational Studies | |
| |
| |
| |
What Are Observational Studies? | |
| |
| |
| |
Some Observational Studies | |
| |
| |
| |
Purpose of This Book | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
References | |
| |
| |
| |
Randomized Experiments | |
| |
| |
| |
Introduction and Example: A Randomized Clinical Trial | |
| |
| |
| |
The Lady Tasting Tea | |
| |
| |
| |
Randomized Experiments | |
| |
| |
| |
Testing the Hypothesis of No Treatment Effect | |
| |
| |
| |
Simple Models for Treatment Effects | |
| |
| |
| |
Confidence Intervals | |
| |
| |
| |
Point Estimates | |
| |
| |
| |
More Complex Outcomes | |
| |
| |
| |
Appendix: Effect Increasing Tests Under Alternatives | |
| |
| |
| |
Appendix: The Set of Treatment Assignments | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Overt Bias in Observational Studies | |
| |
| |
| |
Introduction: An Example and Planning Adjustments | |
| |
| |
| |
Adjustments by Exact Stratification and Matching | |
| |
| |
| |
Case-Referent Studies | |
| |
| |
| |
Small Sample Inference with an Unknown Propensity Score | |
| |
| |
| |
Large Sample Inference with an Unknown Propensity Score | |
| |
| |
| |
Inexact Matching Followed by Stratification | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Sensitivity to Hidden Bias | |
| |
| |
| |
What Is a Sensitivity Analysis? | |
| |
| |
| |
A Model for Sensitivity Analysis | |
| |
| |
| |
Matched Pairs | |
| |
| |
| |
Sensitivity Analysis for Sign-Score Statistics | |
| |
| |
| |
Multiple Controls and Continuous Responses | |
| |
| |
| |
Sensitivity Analysis for Two Unmatched Groups | |
| |
| |
| |
Appendix: Technical Results and Proofs | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Models for Treatment Effects | |
| |
| |
| |
Effects That Vary from Person to Person | |
| |
| |
| |
Order Statistics | |
| |
| |
| |
Dilated Effects | |
| |
| |
| |
Instrumental Variables | |
| |
| |
| |
Attributable Effects: Binary Responses | |
| |
| |
| |
Attributable Effects: Displacements | |
| |
| |
| |
Inference About a Quantile | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
Appendix: Minimum Wage Data | |
| |
| |
| |
References | |
| |
| |
| |
Known Effects | |
| |
| |
| |
Detecting Hidden Bias Using Known Effects | |
| |
| |
| |
An Outcome Known to Be Unaffected by the Treatment | |
| |
| |
| |
An Outcome With Known Direction of Effect | |
| |
| |
| |
The Behavior of T with Nonnegative Effects | |
| |
| |
| |
Bias of Known Direction | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Multiple Reference Groups in Case-Referent Studies | |
| |
| |
| |
Multiple Reference Groups | |
| |
| |
| |
Matched Studies with Two Referent Groups | |
| |
| |
| |
Appendix: Selection and Hidden Bias | |
| |
| |
| |
Appendix: Derivation of Bounds for Sensitivity Analysis | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Multiple Control Groups | |
| |
| |
| |
The Role of a Second Control Group | |
| |
| |
| |
Selecting Control Groups | |
| |
| |
| |
Comparing Outcomes in Two Control Groups | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Coherence and Focused Hypotheses | |
| |
| |
| |
Coherent Associations | |
| |
| |
| |
Signed Rank Statistics for Coherent Predictions | |
| |
| |
| |
Example: Do Anesthetic Gases Cause Mutations? | |
| |
| |
| |
Properties of the Coherent Signed Rank Test | |
| |
| |
| |
Some Other Forms of Coherence | |
| |
| |
| |
Strengths and Limitations of Coherence | |
| |
| |
| |
Appendix: Arrangement-Increasing Functions of Matrices | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Constructing Matched Sets and Strata | |
| |
| |
| |
Introduction: Propensity Scores, Structures, Algorithms | |
| |
| |
| |
The Propensity Score | |
| |
| |
| |
Optimal Strata | |
| |
| |
| |
Optimal Matching | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Software | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Planning an Observational Study | |
| |
| |
| |
Introduction and Some Ground Rules | |
| |
| |
| |
Three Observational Studies | |
| |
| |
| |
Choice of Research Hypothesis | |
| |
| |
| |
A Control Group | |
| |
| |
| |
Defining Treated and Control Groups | |
| |
| |
| |
Competing Theories | |
| |
| |
| |
Internal Replication | |
| |
| |
| |
Nondose Nonresponse: An Absent Association | |
| |
| |
| |
Stability Analyses | |
| |
| |
| |
Abrupt, Short-Lived Treatments | |
| |
| |
| |
Natural Blocks | |
| |
| |
| |
Refute Several Alternative Explanations | |
| |
| |
| |
Bibliographic Notes | |
| |
| |
| |
Problems | |
| |
| |
| |
References | |
| |
| |
| |
Some Strategic Issues | |
| |
| |
| |
What Are Strategic Issues? | |
| |
| |
| |
Some Specific Suggestions | |
| |
| |
| |
References | |
| |
| |
Index | |