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Virus Dynamics Mathematical Principles of Immunology and Virology

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ISBN-10: 0198504179

ISBN-13: 9780198504177

Edition: 2000

Authors: Martin A. Nowak, Robert May

List price: $93.00
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We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how…    
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Book details

List price: $93.00
Copyright year: 2000
Publisher: Oxford University Press, Incorporated
Publication date: 1/25/2001
Binding: Paperback
Pages: 250
Size: 6.14" wide x 9.25" long x 0.55" tall
Weight: 1.980
Language: English

Robert May is Professor of Logic and Philosophy of Science, Linguistics, and Philosophy at the University of California, Irvine. Fiengo and May are the authors of Indices and Identity (MIT Press, 1994).

Introduction: viruses, immunity, equations
HIV
The basic model of virus dynamics
Anti-viral drug therapy
Dynamics of hepatitis B virus
Dynamics of immune responses
How fast do immune responses eliminate infected cells?
What is a quasispecies?
The frequency of resistant mutant virus before anti-viral therapy
Emergence of drug resistance
Timing the emergence of resistance
Simple antigenic variation
Advanced antigenic variation
Multiple epitopes
Everything we know so far and beyond
Dynamics of resistance in different types of infected cells
Analysis of multiple epitope dynamics
References
Index