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ISBN-10: 0123878373

ISBN-13: 9780123878373

Edition: 3rd 2013

Authors: Alan D Michelson

List price: $250.00
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Book details

List price: $250.00
Edition: 3rd
Copyright year: 2013
Publisher: Elsevier Science & Technology
Publication date: 12/10/2012
Binding: Hardcover
Pages: 1398
Size: 9.00" wide x 11.25" long x 2.50" tall
Weight: 8.228
Language: English

A Brief History of Ideas About Platelets in Health and Disease
Platelet Biology
The Evolution of Mammalian Platelets
Megakaryocyte Development and Platelet Formation
The regulation of platelet life span
Platelet Genomics
Platelet MicroRNAs
The Platelet Proteome
Platelet Structure
The Platelet Cytoskeleton
Platelet Receptors
The GPIb-IX-V Complex
Integrin AlphaIIb Beta3
Protease-activated Receptors
The Platelet P2 Receptors
Interactions Between Platelets, Leukocytes and the Endothelium
Inhibition of Platelet Function by the Endothelium
Platelet Secretion
Signal Transduction During Platelet Plug Formation
Platelet Thrombus Formation in Flowing Blood
Interactions Between Platelets and the Coagulation System
Platelet-Derived MicroParticles
The Role of Platelets in Fibrinolysis
The Role of Platelets in Angiogenesis
Platelet Function in the Newborn
Tests of Platelet Function
Clinical Tests of Platelet Function
Platelet Counting
Platelet Aggregation
Flow Cytometry
Monitoring of Antiplatelet Therapy
Real Time In Vivo Imaging of Platelets During Thrombus Formation
The Role of Platelets in Disease
Atherothrombosis and Coronary Artery Disease
Central Nervous System Ischemia
Peripheral Vascular Disease
Diabetes Mellitus
Antimicrobial Host Defense
Tumor Growth and Metastasis
Disorders of Platelet Number and Function
The Clinical Approach to Disorders of Platelet Number and Function
Immune Thrombocytopenia (ITP)
Drug-induced Thrombocytopenia
Heparin-induced Thrombocytopenia
Thrombotic Thrombocytopenic Purpura and the Hemolytic-Uremic Syndrome
Thrombocytopenia in Pregnancy
Thrombocytopenia in the Newborn
Alloimmune Thrombocytopenia
Inherited Thrombocytopenias
Thrombocytosis and Essential Thrombocythemia
Congenital Disorders of Platelet Function
Acquired Disorders of Platelet Function
Cardiopulmonary Bypass
Antiplatelet Therapy
ADP Receptor Antagonists
AlphaIIb Beta3 (GPIIb-IIIa) Antagonists
Novel Antiplatelet Therapies
Therapy to Increase Platelet Numbers and/or Function
Thrombopoietin Mimetics
Factor VIIa
Platelet Transfusion Medicine
Making Platelets Ex Vivo
Gene Therapy for Platelet Disorders