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| Foreword | |
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| Why Stem Cell Research? | |
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| A New Path ? | |
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| Induced Pluripotent Stem Cells | |
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| Embryonic Stem Cells | |
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| Versus Adult Stem Cells | |
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| 'Stemness': Definitions, Criteria and Standards | |
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| Introduction to Stem Cells | |
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| Present Perspective and Future Challenges | |
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| Embryonic Stem Cells in Perspective | |
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| The Development of Epithelial Stem Cell Concepts | |
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| The Advent of Direct Reprogramming | |
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| Clinical Translation of Stem Cells | |
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| Basic Biology Mechanisms | |
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| Molecular Basis of Pluripotency | |
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| Stem Cell Niches | |
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| Mechanisms of Stem Cell Self-Renewal | |
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| Cell Cycle Regulators in Stem Cells | |
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| Epigenetic Mechanisms of Cellular Memory | |
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| Cell Fusion and the Differentiated State | |
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| How Cells Change Their Phenotype | |
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| Tissue and Organ Development | |
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| Differentiation in Early Development | |
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| Primordial Germ Cells in Mouse and Human | |
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| Stem Cells in Extraembryonic Lineages | |
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| Amniotic Fluid Derived Pluripotent Cells | |
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| Cord Blood Stem Cells | |
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| Neurogenesis in the Vertebrate Embryo | |
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| The Nervous System | |
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| Neuronal Progenitors in the Adult Brain | |
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| Sensory Epithelium of the Eye and Ear | |
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| Epithelial Skin Stem Cells | |
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| The Ontogeny of the Hematopoietic System | |
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| Hematopoietic Stem Cells | |
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| Red Blood Cells | |
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| Cell Differentiation in the Skeleton | |
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| Vascular Progenitor Cells | |
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| Multipotent Adult Progenitor Cells | |
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| Mesenchymal Stem Cells | |
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| Skeletal Muscle Stem Cells | |
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| Stem Cells and the Regenerating Heart | |
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| Potential of ES Cell Differentiation Culture for Vascular Biology | |
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| Cell Lineages and Stem Cells in the Kidney | |
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| Adult Liver Stem Cells | |
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| Pancreatic Stem Cells | |
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| Stem Cells in the Gastrointestinal Tract | |
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| Stem Cells in the Lung | |
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| Methods | |
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| Generation of Induced Pluripotent Stem Cells | |
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| Characteristics and Characterization of Pluripotent Stem Cells | |
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| Isolation and Maintenance of Murine Embryonic Stem Cells | |
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| Isolation, Characterization, and Maintenance of Primate ES Cells | |
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| Approaches for Derivation and Maintenance of Human ES cells: Detailed Procedures and Alternatives | |
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| Derivation and Differentiation of Human EG Cells | |
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| Growth Factors & the Serum-Free Culture of Human Pluripotent Stem Cells | |
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| Feeder-Free Culture | |
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| Genetic Manipulation of Human Embryonic Stem Cells | |
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| Homologous Recombination in Human Embryonic Stem Cells | |
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| Surface Antigen Markers | |
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| Lineage Marking | |
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| Genomic Reprogramming | |
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| Isolation and Characterization of Hematopoietic Stem Cells | |
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| Microarray Analysis of Stem Cells and Differentiation | |
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| Zebrafish and Stem Cell Research | |
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| Applications | |
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| Cancer Stem Cells | |
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| Neural Stem Cells: Therapeutic Applications in Neurodegenerative Diseases | |
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| Spinal Cord Injury | |
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| Use of Embryonic Stem Cells to Treat Heart Disease | |
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| Insulin-Producing Cells Derived from Stem Cells: A Potential Treatment for Diabetes | |
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| Burns and Skin Ulcers 978-0-12-370465-8 | |
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| Stem Cells and Heart Disease | |
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| Stem Cells for the Treatment of Muscular Dystropy | |
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| Skin Regeneration | |
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| Orthopaedic Applications of Stem Cells | |
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| Embryonic Stem Cells in Tissue Engineering | |
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| Adult Stem Cells in Tissue Engineering | |
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| Stem Cell Gene Therapy | |
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| Regulation and Ethics | |
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| Ethical Considerations | |
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| Religious Considerations | |
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| Regulatory Considerations | |
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| It�s Not About Curiosity, It�s About Cures | |
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| Epilogue: Concluding Statement | |