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Protein NMR Spectroscopy Principles and Practice

ISBN-10: 012164491X

ISBN-13: 9780121644918

Edition: 2nd 2007 (Revised)

Authors: John Cavanagh, Wayne J. Fairbrother, Arthur G. Palmer, Mark Rance, Nicholas J. Skelton

List price: $121.00
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Description:

Protein NMR Spectroscopycombines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning with simple theoretical models and experimental techniques,Protein NMR Spectroscopydevelops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments. Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. The second edition includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced. Protein NMR Spectroscopyis written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or who wish to understand the latest developments in this field. Provides an understanding of the theoretical principles important for biological NMR spectroscopy Demonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experiments Allows for the capability of designing effective experimental protocols for investigations of protein structures and dynamics Includes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods
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Book details

List price: $121.00
Edition: 2nd
Copyright year: 2007
Publisher: Elsevier Science & Technology Books
Publication date: 12/13/2006
Binding: Hardcover
Pages: 912
Size: 6.25" wide x 9.25" long x 1.75" tall
Weight: 3.542
Language: English

Assical NMR Spectroscopy
Theoretical Description of NMR Spectroscopy
Experimental Aspects of NMR Spectroscopy
Multi-Dimensional NMR Spectroscopy
Relaxation and Dynamic Processes
Experimental 1 H NMR Methods
Heteronuclear NMR Experiments
Sequential Assignments and Structure Calculations
Chapter References
Subject Index