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| Contributors | |
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| Consultants to the Editors | |
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| Preface | |
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| Preface to the First Edition | |
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| General Principles | |
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| Drug Invention and the Pharmaceutical Industry | |
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| Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination | |
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| Pharmacodynamics: Molecular Mechanisms of Drug Action | |
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| Drug Toxicity and Poisoning | |
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| Membrane Transporters and Drug Response | |
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| Drug Metabolism | |
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| Pharmacogenetics | |
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| Neuropharmacology | |
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| Neurotransmission: The Autonomic and Somatic Motor Nervous Systems | |
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| Muscarinic Receptor Agonists | |
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| Anticholinesterase Agents | |
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| Agents Acting at the Neuromuscular Junction and Autonomic Ganglia | |
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| Adrenergic Agonists and Antagonists | |
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| 5-Hydroxytryptamine (Serotonin) and Dopamine | |
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| Neurotransmission and the Central Nervous System | |
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| Drug Therapy of Depression and Anxiety Disorders | |
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| Pharmacotherapy of Psychosis and Mania | |
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| Hypnotics and Sedatives | |
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| Opioids, Analgesia, and Pain Management | |
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| General Anesthetics and Therapeutic Gases | |
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| Local Anesthetics | |
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| Pharmacotherapy of the Epilepsies | |
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| Treatment of Central Nervous System Degenerative Disorders | |
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| Ethanol and Methanol | |
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| Drug Addition | |
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| Modulation of Cardiovascular Function | |
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| Regulation of Renal Function and Vascular Volume | |
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| Renin and Angiotensin | |
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| Treatment of Myocardial Ischemia and Hypertension | |
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| Pharmacotherapy of Congestive Heart Failure | |
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| Anti-Arrhythmic Drugs | |
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| Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs | |
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| Drug Therapy for Hypercholesterolemia and Dyslipiedmia | |
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| Inflammation, Immunomodulation, and Hematopoiesis | |
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| Histamine, Bradykinin, and Their Antagonists | |
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| Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor | |
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| Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacology of Gout | |
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| Immunosupressants, Tolerogens, and Immunostimulants | |
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| Pulmonary Pharmacology | |
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| Hematopoietic Agents: Growth Factors, Minerals, and Vitamins | |
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| Hormones and Hormone Antagonists | |
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| Introduction to Endocrinology: The Hypothalamic-Pituitary Axis | |
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| Thyroid and Anti-Thyroid Drugs | |
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| Estrogens and Progestins | |
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| Androgens | |
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| ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex | |
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| Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia | |
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| Agents Affecting Mineral Ion Homeostatis and Bone Turnover | |
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| Drugs Affecting Gastrointestinal Function | |
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| Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease | |
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| Treatment of Disorders of Bowel Motility and Water Flux: Anti-Emetics; Agents Used in Biliary and Pancreative Disease | |
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| Pharmacotherapy of Inflammatory Bowel Disease | |
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| Chemotherapy of Microbial Diseases | |
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| General Principles of Antimicrobial Therapy | |
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| Chemotherapy of Malaria | |
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| Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections | |
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| Chemotherapy of Helminth Infections | |
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| Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections | |
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| Penicillins, Cephalosporins, and Other à -Lactam Antibiotics | |
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| Aminoglycosides | |
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| Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents | |
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| Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy | |
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| Antifungal Agents | |
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| Antiviral Agents (Nonretroviral), Edward P. Acosta and Charles Flexner | |
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| Antiretroviral Agents and Treatment of HIV Infection | |
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| Chemotherapy of Neoplastic Diseases | |
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| General Principles of Cancer Chemotherapy | |
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| Cytotoxic Agents | |
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| Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines | |
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| Natural Products in Cancer Chemotherapy: Hormones and Related Agents | |
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| Ophthalmology | |
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| Ocular Pharmacology | |
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| Dermatological Pharmacology | |
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| Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders | |
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| Environmental Toxicology: Carcinogens and Heavy Metals | |
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| Appendices | |
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| Principles of Prescription Order Writing and Patient Compliance | |
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| Design and Optimization of Dosage Regimens: Pharmacokinetic Data | |
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| Index | |