Medical Literature A Manual for Evidence-Based Clinical Practice

Name: Medical Literature A Manual for Evidence-Based Clinical Practice
Price: 15.35 USD
Availability: InStock
ISBN: 9780071590341

ISBN-10: 007159034X

ISBN-13: 9780071590341

Edition: 2nd 2008

Authors: Gordon Guyatt, Drummond Rennie, Deborah Cook, Maureen Meade, Maureen Meade

List price: $80.00

30 day, 100% satisfaction guarantee!

Marketplace

3 new & used from $15.35

what's this?

Rush Rewards U
Members Receive:

You have reached 400 XP and carrot coins. That is the daily max!

Description:

The #1 guide to the principles and clinical applications of evidence-based medicine has just gotten better! No other resource helps you to put key evidence-based medicine protocols into daily clinical practice better than "Users' Guides to the Medical Literature," An instant classic in its first edition, this detailed, yet highly readable reference demystifies the statistical, analytical, and clinical principles of evidence-based medicine, giving you a hands-on, practical resource that no other text can match. Here, you'll learn how to distinguish solid medical evidence from poor medical evidence, devise the best search strategies for each clinical question, critically appraise the medical…

Book details

List price: $80.00
Edition: 2nd
Copyright year: 2008
Publisher: McGraw-Hill Professional Publishing
Publication date: 5/21/2008
Binding: Paperback
Pages: 860
Size: 6.00" wide x 9.00" long x 1.50" tall
Weight: 2.244
Language: English

Gordon Guyatt, MD, Deputy Editor, JAMA; Professor of Medicine, McMaster University, Hamilton, Ontario, Canada. Drummond Rennie, MD, Professor of Medicine, UCSF School of Medicine, San Francisco, CA Maureen Meade, MD, Department of Medicine, McMaster University, Hamilton, Ontario, Canada. Deborah Cook, MD, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.



Contributors


Foreword


Preface



The Foundations



How to Use the Medical Literature-and This Book-to Improve Your Patient Care



The Philosophy of Evidence-Based Medicine



What Is the Question?



Finding the Evidence



Why Study Results Mislead: Bias and Random Error



Therapy



Therapy (Randomized Trials)



Does Treatment Lower Risk? Understanding the Results



Confidence Intervals



Advanced Topics in the Validity of Therapy Trials



An Illustration of Bias and Random Error



Surprising Results of Randomized Trials



Randomized Trials Stopped Early for Benefit



The Principle of Intention to Treat



N-of-1 Randomized Controlled Trials



Clinical Decision Support Systems



Advanced Topics in the Results of Therapy Trials



Hypothesis Testing



Understanding the Results: More About Odds Ratios



What Determines the Width of the Confidence Interval?



Composite Endpoints



Measuring Patients' Experience



Advanced Topics in Applying the Results of Therapy Trials



Applying Results to Individual Patients



Example Numbers Needed to Treat



Dealing With Misleading Presentations of Clinical Trial Results



Surrogate Outcomes



Qualitative Research



Harm (Observational Studies)



Harm (Observational Studies)



Advanced Topics in Harm: Correlation and Regression



Diagnosis



The Process of Diagnosis



Differential Diagnosis



Diagnostic Tests



Advanced Topics in Diagnosis



Spectrum Bias



Examples of Likelihood Ratios



Measuring Agreement Beyond Chance



Clinical Prediction Rules



Prognosis



Prognosis



Summarizing the Evidence



Summarizing the Evidence



Advanced Topics in Systematic Reviews



Reporting Bias



Fixed-Effects and Random-Effects Models



Making Sense of Variability in Study Results



When to Believe a Subgroup Analysis



Moving From Evidence to Action



How to Use a Patient Management Recommendation



Advanced Topics in Moving From Evidence to Action



Economic Analysis



Decision Making and the Patient



Moving From Evidence to Action: Recommendations About Screening



Grading Recommendations



Drug Class Effects



Parallel but Separate Goals: Evidence-Based Practitioners and Evidence-Based Care



Changing Behavior to Apply Best Evidence in Practice



Teachers' Guides to the Users' Guides


Glossary


Index