Androgen Receptor Modulation in Prostate Cancer

Name: Androgen Receptor Modulation in Prostate Cancer
Price: 58.97 USD
Availability: InStock
ISBN: 9783838352473

ISBN-10: 3838352475

ISBN-13: 9783838352473

Edition: N/A

Authors: Peyman Tavassoli

List price: $73.00

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Description:

There is considerable evidence to suggest that progression of prostate cancers to castration- resistant is due to inappropriate activation of the androgen receptor (AR) and hence, the AR is a good target for the treatment of this disease. In this study we used two approaches to investigate AR activation and inhibition. We developed high-throughput, non-invasive, cell- based screening assays to rapidly and biologically assess factors that modulate prostate cancer growth and affect AR activity. Using these assays, we found that differentiated osteoblast-like condition media enhanced prostate cancer cell growth, but not AR activity. In addition, we applied this system to screen compounds,…

Book details

List price: $73.00
Publisher: Lambert Academic Publishing
Binding: Paperback
Pages: 148
Size: 6.00" wide x 9.00" long x 0.34" tall
Weight: 0.506
Language: English