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Human Diabetes Genetic, Environmental and Autoimmune Etiology

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ISBN-10: 364275743X

ISBN-13: 9783642757433

Edition: 1990

Authors: Steinunn Baekkeskov, Bruno Hansen

List price: $109.99
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Description:

Insulin dependent diabetes mellitus, IDDM, develops primarily in genetically predisposed individuals under the influence of autoimmune or environmental factors. This volume brings together the latest knowledge of all factors which are involved in the destruction of the pancreatic -cell and thus lead to IDDM. Section I on genetics provides an up to date review of the characterization of the role of MHC-class II alleles in this disease and the structural dissection of susceptibility genes in this region with particular emphasis on the role of Asp 57 in HLA-DQ. Section II on the etiology of -cell destruction deals with mechanisms of generation of tolerance to -cell antigens and the possible…    
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Book details

List price: $109.99
Copyright year: 1990
Publisher: Springer Berlin / Heidelberg
Publication date: 12/10/2011
Binding: Paperback
Pages: 198
Size: 6.10" wide x 9.25" long x 0.18" tall
Weight: 0.748
Language: English