Iron Acquisition by the Genus Mycobacterium History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development

Name: Iron Acquisition by the Genus Mycobacterium History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development
Price: 35.75 USD
Availability: InStock
ISBN: 9783319003023

ISBN-10: 331900302X

ISBN-13: 9783319003023

Edition: 2013

Authors: B. Rowe Byers

List price: $54.99

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Description:

Iron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described. The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed. The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs…

Book details

List price: $54.99
Copyright year: 2013
Publisher: Springer International Publishing AG
Publication date: 6/3/2013
Binding: Paperback
Pages: 92
Size: 6.10" wide x 9.25" long x 0.25" tall
Weight: 0.374
Language: English