Basic Concepts in Medicinal Chemistry

Name: Basic Concepts in Medicinal Chemistry
Price: 11.7 USD
Availability: InStock
ISBN: 9781585282661

ISBN-10: 1585282669

ISBN-13: 9781585282661

Edition: 2013

Authors: Marc W. Harrold, Robin M. Zavod, American Society of Health-System Pharmacists Staff

List price: $60.00

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Description:

Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are…

Book details

List price: $60.00
Copyright year: 2013
Publisher: American Society of Health-System Pharmacists
Publication date: 1/18/2013
Binding: Paperback
Pages: 460
Size: 7.00" wide x 9.75" long x 0.75" tall
Weight: 1.782
Language: English



Acknowledgments


Preface


Abbreviations Used in This Text


About the Authors



Introduction



Functional Group Characteristics and Roles



Identifying Acidic and Basic Functional Groups



Solving pH and pK<sub>a</sub> Problems



Salts and Solubility



Drug Binding Interactions



Stereochemistry and Drug Action



Drug Metabolism



Structure Activity Relationships and Basic Concepts in Drug Design


Appendix: Questions and Answers


Index