Introduction to Biomems

ISBN-10: 1439818398

ISBN-13: 9781439818398

Edition: 2012

Authors: Albert Folch

List price: $140.99
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Providing a fundamental introduction to the use of micro-electromechanical techniques for the design and fabrication of biomedical devices, this work discusses miniaturization through optical, fluidic, biological, and/or nanoscale methods. It begins with basic microfabrication techniques and the micropatterning of biomolecules, polymers, and cells. It then discusses microfluidic, lab-on-a-chip, and cell-based approaches. The author also covers cell biology, tissue engineering, implants and sensors, and emerging applications, such as microfluidics foundries, plug-and-play devices, and self-assembled nanodevices. The text includes text boxes for definitions, design challenges, and reading assignments.
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Book details

List price: $140.99
Copyright year: 2012
Publisher: CRC Press LLC
Publication date: 8/21/2012
Binding: Hardcover
Pages: 528
Size: 7.75" wide x 10.00" long x 1.00" tall
Weight: 3.344
Language: English

How Do We Make Small Things?
Why Bother Making Things Small?
From Art to Chips
Soft Lithography
Hydrogel Devices
Nanofabrication Techniques
Fabrication Based on Self-Assembly: A "Bottom-Up" Approach
Micropatterning of Substrates and Cells
Interaction between Surfaces and Biomolecules
Surface Engineering
Micropatterns of SAMs
Micropatterns of Proteins
Micropatterns of Cells on Nonbiomolecular Templates
Micropatterns of Cells on Biomolecular Templates
Why Go Small?
Microscale Behavior of Fluids
Fluids in Electrical Fields
Fluids in Acoustic Fields
Fabrication of Microfluidic Channels
Operation of Microfluidic Channels: Practical Concerns
Droplet Microfluidics
Active Flow Control
Combinatorial Mixers
Molecular Biology on a Chip
The Importance of Miniaturizing Molecular Biology
The Importance of Point-of-Care Diagnostics: Where is Cost Really, Really, Really Important?
Sample Preparation: A Bloody Example
The Problem with Microfluidic Sample Separation
Microfluidic Immunoassays
Chips for Genomics and Proteomics
Electrospray Mass Spectrometry
Biochemical Analysis Using Force Sensors
Cell-Based Chips for Biotechnology
Microfluidic Flow Cytometers
Cell Sorting
Cell Trapping
Microfluidic Cell Culture Laboratories
Gene Expression Cellular Microarrays ("Cellomics")
Cells on Microelectrodes
Patch Clamp Chips
Assisted Reproductive Technologies
Whole Animal Testing
BioMEMS for Cell Biology
An Enabling Technology: The Hurdles
Cell-Substrate Signaling
Cell-Cell Communication
Cell Migration
BioMEMS for Cellular Neurobiology
Developmental Biology on a Chip
Yeast Biology
Plant Cell Biology
Microfluidics for Studying Cellular Dynamics
Tissue Microengineering
Micropatterned Cocultures
Stem Cell Engineering
Implantable Microdevices
Dental Implants
Implantable Microelectrodes
Delivery of Soluble Signals into the Body
Microtools for Surgery
Insect Research
A Summary and Further Reading appear at the end of each chapter
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