From DNA to Diversity Molecular Genetics and the Evolution of Animal Design

ISBN-10: 1405119500
ISBN-13: 9781405119504
Edition: 2nd 2004 (Revised)
List price: $112.95 Buy it from $10.74
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Description: In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second  More...

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Book details

List price: $112.95
Edition: 2nd
Copyright year: 2004
Publisher: John Wiley & Sons, Incorporated
Publication date: 10/22/2004
Binding: Paperback
Pages: 268
Size: 7.50" wide x 9.75" long x 0.75" tall
Weight: 1.650
Language: English

In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development. An accessible text, focusing on the most well-known genes, developmental processes and taxa. Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels. Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species. Provides in-depth focus on key concepts through well-developed case studies. Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary. Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology.

Preface
A Brief History of Animals
Animal origins and the fossil record
The animal tree
General features of animal design and diversity
Evolution and development: DNA and diversity
The Genetic Toolkit for Development
Before the toolkit-organizers, fields, and morphogens
The genetic toolkit
Sharing of the genetic toolkit among animals
The toolkit and animal design
Building Animals
Gene regulation in metazoans
The architecture of genetic regulatory hierarchies
The insect body plan
The vertebrate body plan
Review: the general logic and mechanisms controlling gene expression in cellular fields
Evolution of the Toolkit
The history of gene families
Case study: evolution of the Hox complex
Interpreting the toolkit: inferences about animal evolution
The toolkit as developmental potential
Diversification of Body Plans and Body Parts
Diversity of anterior/posterior body organization within arthropods and vertebrates
Morphological diversity within a conserved body plan
Regulatory evolution and the diversification of homologous body parts
The Evolution of Morphological Novelties
What is morphological novelty?
Novel functions from older morphological structures
The evolution of vertebrate novelties
Evolution of radical body plan changes
Regulatory evolution and the origin of novelties
Morphological Variation and Species Divergence
Evolution of animal color patterns
Nodal points in regulatory networks and the evolution of character number and pattern
Qualitative and quantitative aspects of skeletal evolution in stickleback fish
More variation than meets the eye: cryptic genetic variation and the potential for morphological evolution
Regulatory evolution and species divergence
From DNA to Diversity: The Primacy of Regulatory Evolution
Why is regulatory evolution a primary force in morphological evolution?
The function and evolution of cis-regulatory DNA
The evolution of regulatory DNA and morphological diversity
Glossary
Index

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