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| Foreword | |
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| Preface | |
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| Editors | |
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| Advisory Committee to the Editors | |
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| Contributors | |
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| Disease Control Priorities Project Partners | |
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| Acknowledgments | |
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| Abbreviations and Acronyms | |
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| Measuring the Global Burden of Disease and Risk Factors, 1990-2001 | |
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| History of Burden of Disease Studies | |
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| Applications of Burden of Disease Analysis | |
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| Improving the Comparative Quantification of Diseases, Injuries, and Risk Factors: The 2001 GBD Study | |
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| Major Findings of the 2001 GBD Study | |
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| Conclusions | |
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| References | |
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| Global Burden of Disease and Risk Factors | |
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| Demographic and Epidemiological Characteristics of Major Regions, 1990-2001 | |
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| Regional Demographic Characteristics | |
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| Changes in Mortality, 1990-2001 | |
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| Trends in Causes of Child Death, 1990-2001 | |
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| Discussion | |
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| Conclusions | |
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| Key Demographic Indicators, by Country/Territory, 1990 and 2001 | |
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| Acknowledgments | |
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| Notes | |
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| References | |
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| The Burden of Disease and Mortality by Condition: Data, Methods, and Results for 2001 | |
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| Quantifying the Global Burden of Disease | |
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| Estimating Deaths by Cause: Methods and Data | |
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| Global and Regional Mortality in 2001 | |
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| Estimating Incidence, Prevalence, and YLD: Methods and Data | |
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| Burden of Disability and Poor Health in 2001 | |
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| Global Burden of Disease in 2001 | |
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| Discussion and Conclusions | |
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| Definitions, Mortality Data Sources, and Disability Weights | |
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| Deaths by Cause, Sex, Age, and Region, 2001 | |
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| DALYs (3,0) by Cause, Sex, Age, and Region, 2001 | |
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| Acknowledgments | |
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| References | |
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| Comparative Quantification of Mortality and Burden of Disease Attributable to Selected Risk Factors | |
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| Burden of Disease Attributable to Risk Factors | |
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| Risk Factor Selection | |
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| Burden of Disease Attributable to Individual Risk Factors | |
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| Joint Effects of Multiple Risk Factors | |
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| Burden of Disease Attributable to Multiple Risk Factors | |
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| Directions for Future Research | |
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| Discussion | |
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| Population Attributable Fractions, Attributable Deaths, Years of Life Lost Because of Premature Mortality (YLL), and Disability-Adjusted Life Years (DALYs) by Risk Factor, Disease Outcome, Age, Sex, and Region | |
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| References | |
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| Sensitivity Analyses | |
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| Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates | |
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| Discounting and Age Weighting in the DALY Measure | |
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| Sensitivity of Burden of Disease and Injury Results to Variations in Key Parameter Values | |
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| Sensitivity of Risk Factor Estimates to Variations in Key Parameter Values | |
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| Uncertainty Analysis of the Global Burden of Disease Estimates | |
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| Uncertainty Estimates for All-Cause Mortality and Life Expectancies | |
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| Uncertainty Estimates for Regional Mortality by Cause | |
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| Uncertainty in Disability Weights | |
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| Uncertainty Arising from Epidemiological Estimates | |
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| Uncertainty in the Disease Burden Attributable to Risk Factors | |
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| Discussion | |
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| Conclusions | |
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| Acknowledgments | |
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| References | |
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| Incorporating Deaths Near the Time of Birth into Estimates of the Global Burden of Disease | |
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| Stillbirths and Neonatal Mortality in the Context of the Global Burden of Disease | |
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| The Burden of Disease Resulting from Events Near the Time of Birth | |
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| Conclusions | |
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| Flexible Functional Forms for the Acquisition of Life Potential | |
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| Supplementary Tables | |
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| Causes of Neonatal Mortality: Comparison of Numbers from the Global Burden of Disease with those from the Child Health Epidemiology Reference Group | |
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| Acknowledgments | |
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| References | |
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| List of Boxes | |
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| Disability-Adjusted Life Years | |
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| List of Figures | |
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| Overview of Burden of Disease Framework | |
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| Changes in Population Age Distribution, 1990-2001 | |
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| Population Sex Ratios at Different Ages, 2001 | |
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| UN's versus Authors' Life Table Parameters, 1990 | |
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| Change in Risk of Death for Children Under Five by Cause (probability of mortality per 1,000 live births), 1990-2001 | |
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| Relationship between Health Expectancies and Health Gaps in a Stationary Population | |
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| Variation across Selected Countries in Coding for Ill-Defined CVD Causes, 1979-98 | |
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| Mortality Rates for Socioeconomic Strata, by Cause Group, from China's Two Mortality Data Systems | |
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| CodMod Estimation of Major Cause Group Proportional Mortality for Islamic Republic of Iran, 2001 | |
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| Proportional Distribution of Total Deaths by Broad Cause Group, 2001 | |
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| Death Rates by Broad Cause Group, Region, and Broad Age Group, 2001 | |
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| Leading Causes of Premature Death (YLL) and of Deaths, Worldwide, 2001 | |
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| Disease Model Underlying DisMod | |
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| Input Prevalences and Incidence Rates Estimated Using DisMod II, for Diabetes Mellitus Cases in Males, Sub-Saharan Africa | |
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| Life Expectancy, HALE, and Lost Healthy Years by Region and Sex, 2001 | |
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| YLL, YLD, and DALYs by Region, 2001 | |
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| Burden of Disease by Broad Cause Group and Region, 2001 | |
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| Age Distribution of Burden of Disease by Income Group, 2001 | |
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| Mortality and the Burden of Disease Attributable to Leading Global Risk Factors, by World Bank Region | |
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| Burden of Disease Attributable to 10 Leading Regional Risk Factors, by Disease Type | |
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| Mediated and Direct Effects of a Risk Factor | |
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| Age-Weighting Function Incorporated into the DALY | |
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| Effect of Age Weighting and Discounting on the YLL per Death at Various Ages for Females | |