Principles of Proteomics

ISBN-10: 0815344724
ISBN-13: 9780815344728
Edition: 2nd 2014 (Revised)
Authors: Richard Twyman
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Description: Principles of Proteomics, Second Edition explains and demystifies the key challenges faced by someone studying the field of proteomics by encouraging an understanding in the fundamental aspects of this field.Proteomics is about the global analysis  More...

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Book details

List price: $104.00
Edition: 2nd
Copyright year: 2014
Publisher: Taylor & Francis Group
Publication date: 9/16/2013
Binding: Paperback
Pages: 260
Size: 8.25" wide x 10.00" long x 0.50" tall
Weight: 1.232
Language: English

Principles of Proteomics, Second Edition explains and demystifies the key challenges faced by someone studying the field of proteomics by encouraging an understanding in the fundamental aspects of this field.Proteomics is about the global analysis of proteins. It seeks to achieve what genomics cannot: a complete description of living cells in terms of all their functional components, brought about by the direct analysis of those components rather than the genes that encode them.Although now firmly established, proteomics is still difficult to penetrate for those not used to the terminology and technology involved. There is still a great deal of jargon, many acronyms and a high turnover of methods at the cutting edge. As with the first edition, this book will be useful to those who need a broad overview of proteomics and what it has to offer. The aim of this book is to pull together a lot of disparate information concerning the different proteomics technologies and their applications, and present them in a simple and user-friendly manner.In this book the various proteomic technologies are discussed in detail: two-dimensional gel electrophoresis, multidimensional liquid chromatography, mass spectrometry, sequence analysis, structural analysis, and methods for studying protein interactions, modifications, localization and function. The chapters on liquid chromatography and mass spectrometry include new developments, particularly in the area of quantitative proteomics. New sections deal with the increasingly prevalent field of subcellular proteomics, including organelle proteomics, membrane proteomics and the proteomic analysis of chemically defined subfractions of the cell. Due to the prodigious developments in protein chips in the last 5 years this topic is given special coverage.

The Origin and Scope of Proteomics
Strategies for Protein Separation
Strategies for Protein Identification
Strategies for Protein Quantitation
The Analysis of Protein Sequences
The Analysis of Protein Structures
Interaction Proteomics
Protein Modification in Proteomics
Protein Microarrays
Applications of Proteomics

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