Human Molecular Genetics

ISBN-10: 0815341490
ISBN-13: 9780815341499
Edition: 4th 2010 (Revised)
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Book details

List price: $155.00
Edition: 4th
Copyright year: 2010
Publisher: Taylor & Francis Group
Publication date: 4/2/2010
Binding: Paperback
Pages: 808
Size: 8.00" wide x 10.00" long x 1.25" tall
Weight: 2.794
Language: English

Tom Strachan is Scientific Director of the Institute of Human Genetics and Professor of Human Molecular Genetics at Newcastle University, UK, and is a Fellow of the Academy of Medical Sciences and a Fellow of the Royal Society of Edinburgh. Tom's early research interests were in multigene family evolution and interlocus sequence exchange, notably in the HLA and 21-hydroxylase gene clusters. While pursuing the latter, he became interested in medical genetics and disorders of development. His most recent research has focused on developmental control of the vertebrate cohesion regulators Nipbl and Mau-2.Andrew Read is Emeritus Professor of Human Genetics at the University of Manchester, UK and a Fellow of the Academy of Medical Sciences. Andrew has been particularly concerned with making the benefits of DNA technology available to people with genetic problems. He established one of the first DNA diagnostic laboratories in the UK over 20 years ago (it is now one of two National Genetics Reference Laboratories), and was founder chairman of the British Society for Human Genetics, the main professional body in this area. His own research is on the molecular pathology of various hereditary syndromes, especially hereditary hearing loss.Drs. Strachan and Read were recipients of the European Society of Human Genetics Education Award.

The Basics of DNA, Chromosomes, Cells, and Development
Nucleic Acid Structure and Gene Expression
Chromosome Structure and Function
Genes in Pedigrees and Populations
Cells and Cell-Cell Communication
Principles of Development
Analyzing the Structure and Expression of Genes and Genomes
Amplifying DNA: Cell-based DNA Cloning and PCR
Nucleic Acid Hybridization: Principles and Applications
Analyzing the Structure and Expression of Genes and Genomes
Investigating the Human Genome and its Relationship to Other Genomes
Organization of the Human Genome
Model Organisms, Comparative Genomics and Evolution
Human Gene Expression
Studying Gene Function in the Post-Genome Era
Human Genetic Variation and Diseases
Human Genetic Variability and its Consequences
Genetic Mapping of Mendelian Characters
Mapping Genes Conferring Susceptibility to Complex Disease
Identifying Human Disease Genes and Susceptibility Factors
Cancer Genetics
Applied Human Molecular Genetics
Genetic Testing of Individuals
Pharmacogenetics, Personalized Medicine, and Population Screening
Genetic Manipulation of Animals for Modeling Disease and Investigating Gene Function
Genetic Approaches to Treating Disease
Glossary
Index

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