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Exercise Biochemistry

ISBN-10: 0736056386
ISBN-13: 9780736056380
Edition: 2006
Authors: Vassilis Mougios
List price: $116.00 Buy it from $28.31
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Description: This text is heavily illustrated throughout, and provides biochemistry basics as well as in-depth coverage of exercise biochemistry. Textbook elements such as key terms are highlighted in the text and defined in the glossary and sidebars. Questions  More...

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Book details

List price: $116.00
Copyright year: 2006
Publisher: Human Kinetics Publishers
Publication date: 6/2/2006
Binding: Paperback
Pages: 352
Size: 8.50" wide x 11.00" long x 1.00" tall
Weight: 2.882
Language: English

This text is heavily illustrated throughout, and provides biochemistry basics as well as in-depth coverage of exercise biochemistry. Textbook elements such as key terms are highlighted in the text and defined in the glossary and sidebars. Questions and problems are given at the end of each chapter.

Preface
A Guided Tour for the Student
Biochemistry Basics
Introduction
Chemical Elements
Chemical Bonds
Molecules
Ions
Polarity Influences Miscibility
Solutions
Chemical Reactions and Equilibrium
pH
Acid-Base Interconversions
Classes of Biological Substances
Cell Structure
Problems and Critical Thinking Questions
Metabolism
Free-Energy Changes Earmark Metabolic Reactions
Determinants of Free-Energy Change
ATP, the Energy Currency of Cells
Phases of Metabolism
Oxidation-Reduction Reactions
Overview of Catabolism
Problems and Critical Thinking Questions
Proteins
Amino Acids
The Peptide Bond
Primary Structure of Proteins
Secondary Structure
Tertiary Structure
Denaturation
Quaternary Structure
Protein Function
Oxygen Carriers
Myoglobin
Hemoglobin
The Wondrous Properties of Hemoglobin
Enzymes
The Active Site
Enzymes Affect the Rate but not the Direction of Reactions
Factors Affecting the Rate of Enzyme Reactions
Problems and Critical Thinking Questions
Nucleic Acids and Gene Expression
Introducing Nucleic Acids
Flow of Genetic Information
Deoxyribonucleotides, the Building Blocks of DNA
Primary Structure of DNA
The Double Helix of DNA
The Genome of Living Organisms
DNA Replication
Mutations
RNA
Transcription
Genes and Gene Expression
Messenger RNA
Translation
The Genetic Code
Transfer RNA
Translation Continued
In The Beginning, RNA?
Problems and Critical Thinking Questions
Carbohydrates and Lipids
Carbohydrates
Monosaccharides
Oligosaccharides
Polysaccharides
Lipids
Fatty Acids
Triacylglycerols
Phospholipids
Steroids
Cell Membranes
Problems and Critical Thinking Questions
Part I Summary
Biochemistry of the Neural and Muscular Processes of Movement
Neural Control of Movement
Nerve Signals Are Transmitted in Two Ways
The Resting Potential
The Action Potential
Propagation of an Action Potential
Transmission of a Nerve Impulse from One Neuron to Another
Birth of a Nerve Impulse
The Neuromuscular Junction
A Lethal Arsenal at the Service of Research
Problems and Critical Thinking Questions
Muscle Contraction
Structure of a Muscle Cell
The Sliding-Filament Theory
The Wondrous Properties of Myosin
Structure of Myosin
Actin
Sarcomere Architecture
Mechanism of Force Generation
Myosin Isoforms and Muscle Fiber Types
Control of Muscle Contraction
Excitation-Contraction Coupling
Problems and Critical Thinking Questions
Part II Summary
Exercise Metabolism
Principles of Exercise Metabolism
Exercise Parameters
Experimental Models Used to Study Exercise Metabolism
Five Means of Metabolic Control in Exercise
Four Classes of Energy Sources in Exercise
Compounds of High Phosphoryl Transfer Potential
The ATP-ADP Cycle
The ATP-ADP Cycle in Exercise
Creatine Phosphate
Window to the Sarcoplasm
Loss of AMP by Deamination
Problems and Critical Thinking Questions
Carbohydrate Metabolism in Exercise
Glycogen Metabolism
Exercise Speeds up Glycogenolysis in Muscle
The Cyclic-AMP Cascade
Recapping the Effect of Exercise on Glycogen Metabolism
Glycolysis
Exercise Speeds up Glycolysis in Muscle
Pyruvate Oxidation
Exercise Speeds up Pyruvate Oxidation in Muscle
The Citric Acid Cycle
Exercise Speeds up the Citric Acid Cycle in Muscle
The Electron Transport Chain
Oxidative Phosphorylation
Energy Yield of the Electron Transport Chain
Energy Yield of Carbohydrate Oxidation
Exercise Speeds up Oxidative Phosphorylation in Muscle
Lactate Production in Muscle During Exercise
Features of the Anaerobic Carbohydrate Catabolism
Utilizing Lactate
Gluconeogenesis
Exercise Speeds up Gluconeogenesis in the Liver
The Cori Cycle
Exercise Speeds up Glycogenolysis in the Liver
Control of the Plasma Glucose Concentration in Exercise
Blood Lactate Accumulation
Blood Lactate Removal
"Thresholds"
Problems and Critical Thinking Questions
Lipid Metabolism in Exercise
Triacylglycerol Metabolism in Adipose Tissue
Exercise Speeds up Lipolysis
Fate of the Lipolytic Products During Exercise
Fatty Acid Degradation
Energy Yield of Fatty Acid Oxidation
Fatty Acid Synthesis
Exercise Speeds up Fatty Acid Oxidation in Muscle
Changes in the Plasma Fatty Acid Concentration and Profile During Exercise
Interconversion of Lipids and Carbohydrates
Plasma Lipoproteins
A Lipoprotein Odyssey
Effects of Exercise on Plasma Triacylglycerols
Effects of Exercise on Plasma Cholesterol
Exercise Increases Ketone Body Formation
Problems and Critical Thinking Questions
Protein Metabolism in Exercise
Protein Metabolism
Effect of Exercise on Protein Metabolism
Amino Acid Metabolism in Muscle During Exercise
Amino Acid Metabolism in the Liver During Exercise
The Urea Cycle
Amino Acid Synthesis
Plasma Amino Acid, Ammonia, and Urea Concentrations During Exercise
Contribution of Proteins to the Energy Expenditure of Exercise
Effects of Training on Protein Metabolism
Critical Thinking Questions
Effects of Exercise on Gene Expression
Stages in the Control of Gene Expression
Which Stages in the Control of Gene Expression Does Exercise Affect?
Kinetics of a Gene Product After Exercise
Exercise-Induced Changes that May Modify Gene Expression
Mechanisms of Exercise-Induced Muscle Hypertrophy
Mechanisms of Exercise-Induced Mitochondrial Biogenesis
Problems and Critical Thinking Questions
Integration of Exercise Metabolism
Interconnections of Metabolic Pathways
Energy Systems
Energy Sources in Exercise
Choice of Energy Sources During Exercise
Effect of Exercise Intensity on the Choice of Energy Sources
Effect of Exercise Duration on the Choice of Energy Sources
Interaction of Duration and Intensity: Energy Sources in Running and Swimming
Effect of the Exercise Program on the Choice of Energy Sources
Effect of Heredity on the Choice of Energy Sources in Exercise
Conversions of Muscle Fiber Types
Effect of Nutrition on the Choice of Energy Sources During Exercise
Adaptations of the Proportion of Energy Sources During Exercise to Endurance Training
How Does Endurance Training Modify the Proportion of Energy Sources During Exercise?
Adaptations of Energy Metabolism to Anaerobic Training
Effect of Age on the Choice of Energy Sources During Exercise
Do Sex and Ambient Temperature Affect the Choice of Energy Sources During Exercise?
The Proportion of Fuels Can Be Measured Bloodlessly
Hormonal Effects on Exercise Metabolism
Fatigue
Central Fatigue
Peripheral Fatigue
Restoration of the Energy State After Exercise
Metabolic Changes in Detraining
Problems and Critical Thinking Questions
Part III Summary
Biochemical Assessment of Exercising Persons
The Blood
Aims and Scope of the Biochemical Assessment
The Reference Interval
Classes of Biochemical Parameters
Iron Status
Hemoglobin
Hematologic Parameters
Does Sports Anemia Exist?
Iron
Total Iron-Binding Capacity
Transferrin Saturation
Soluble Transferrin Receptor
Ferritin
Iron Deficiency
Problems and Critical Thinking Questions
Metabolites
Lactate
Estimating the Anaerobic Lactic Capacity
Programming Training
Estimating Aerobic Endurance
Glucose
Triacylglycerols
Cholesterol
HDL Cholesterol
LDL Cholesterol
Recapping Cholesterol
Glycerol
Urea
Ammonia
Creatinine
Problems and Critical Thinking Questions
Enzymes and Hormones
Enzymes
Creatine Kinase
Aminotransferases
Steroid Hormones
Cortisol
Testosterone
Overtraining
Epilogue
Problems and Critical Thinking Questions
Part IV Summary
References
Suggested Readings
Answers to Problems and Critical Thinking Questions
Glossary
Index
About the Author

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