Anesthetic Pharmacology Basic Principles and Clinical Practice

ISBN-10: 0521896665

ISBN-13: 9780521896665

Edition: 2nd 2011

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Book details

List price: $268.00
Edition: 2nd
Copyright year: 2011
Publisher: Cambridge University Press
Publication date: 3/10/2011
Binding: Box or Slipcased 
Pages: 1262
Size: 9.00" wide x 11.25" long x 2.50" tall
Weight: 9.988
Language: English

Some business authors are merely glorified journalists who interviewed a large number of business owners and then came up with their own conclusions. Mr. Denis Nurmela on the other hand, is someone who has actually built companies from the ground up. He has experienced multimillion dollar business revenue success as well as learned from business failures.Denis began his first nonprofit business when he was nine years old. It was a neighborhood ecology club that did newspaper, aluminum, and glass bottle recycling. Even as a young man, when Denis served in the United States Air Force and when he worked many years as a surgical technician, he continued to run at least a one side business.Mr. Nurmela founded and ran a variety of companies. One was an emergency alert software system that was designed for military recall, substitute teacher notification and public emergency related responses. Mr. Nurmela represented his company as a member of a congressional advisory committee for the United States emergency alert system.He was also founder and executive director of a human tissue surgical recovery service. This was not your typical business to begin as a start-up. As you can imagine it was highly regulated by state and federal agencies including the FDA, OSHA, and was accredited by the American Association of tissue Banks.Denis and his wife Cindy have lived in the same small town in Southern California since 1987. They have raised six children some of which have already started blessing them with grandchildren. They own just over 5 acres where they enjoy growing a garden, maintaining a small fruit orchard, and raising a variety of animals including chickens to give them fresh eggs every day.Mr. Nurmela is a sought after business consultant, coach, corporate trainer/speaker, and strategic plan facilitator. He is also an accomplished freelance business writer and is a part-time college business professor. He oversees the Saturday morning CEO boot camp, video business tip subscription service, radio show, online training classes and mastermind groups which can all be accessed at www.SaturdayMorningCEO.comDenis Nurmela loves teaching and this is why management college students love him. He wrote this book, co-hosts a radio show, runs a boot camp, and oversees mastermind groups because he really loves teaching business owners and executive level leaders. His desire to serve others is his source of passion for what he does.

Professor Mervyn Maze is Chair, Department of Anesthesia and Perioperative Care, University of California, San Francisco, USA.

Evan Kharasch is Russell D. and Mary B. Shelden Professor of Anesthesiology, Director, Division of Clinical and Translational Research, Department of Anesthesiology, and Professor of Biochemistry and Molecular Biophysics, Washington University, USA.

Preface to the first edition
Preface to the second edition
Principles of Drug Action
Pharmacodynamic principles of drug action
G protein coupled receptors
Other signalling pathways
Signal transduction mechanisms: ion channels
Principles of pharmacokinetics
Principles of drug transformation
Drug transport and transporters
Target controlled infusions and closed loop administration
Alternate routes of drug administration
Principles of pharmacogenetics
Pharmacodynamic drug interactions in anesthetic practice
Pharmacoeconomics
Physiologic Substrates of Drug Action
Sleep and consciousness
Synaptic transmission
Memory, learning and cognition
Mechanisms of pain transmission and transduction
Generation and propagation of action potentials
Neuromuscular junction
Vascular reactivity
Cardiac rhythm
Myocardial performance
Autonomic function
Physiology of immunity and inflammation
Essential Drugs in Anesthetic Practice
Mechanisms of anesthetic action
Pharmacokinetics of inhaled anesthetics
Clinical pharmacology of inhaled anesthetics
Pharmacokinetics of intravenous anesthetics
Clinical pharmacology of intravenous anesthetics
Benzodiazepines
�-2 Agonists and other sedatives and amnestics
Mechanisms of action of opioids
Pharmacokinetics of opioids
Clinical pharmacology of opioids
Nonsteroidal anti-inflammatory drugs
Other ion channel and receptor ligands for analgesia
Local anesthetics
Anticonvulsant and antipsychotic drugs
Neuromuscular blocking agents
Reversal drugs
Sympathomimetics and vasoconstrictors
Parasympathomimetic and parasympatholytic drugs
�-blockers and other adrenergic receptor antagonists
Antiarrhythmic agents
Positive inotropic drugs
Vasodilators (incl. ACE inhibitors and NO)
Calcium channel blockers
Bronchodilators
Pulmonary vasodilators
Drugs acting via the kidney
Fluids and electrolytes as pharmacologic agents
Corticosteroids and anti-inflammatory agents
Anti-rejection drugs and immunosuppressants
Antimotility and antisecretory agents
Antiemetics
Insulin and anti-hyperglycemic agents
Nutritional elements of management
Agents affecting coagulation and platelet function
Obstetrical adjuvants and obstetric pharmacology
Antimicrobial therapy
Clinical Application and Anesthesia Practice (Evidence Based, Rational Drug Selection, Management)
Pre-operative management
Induction of anesthesia
Maintenance and emergence from anesthesia
Management of sedation, analgesia and delirium
Post-operative analgesia
Control of blood pressure and vascular tone
Cardiac protection and pharmacologic management of myocardial ischemia
Management of patients with chronic alcohol or drug use
Drug allergy and treatment
Special populations - pediatric
Special populations - geriatric
Emerging concepts: neuroprotection and neurotoxicity
Index
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