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Anesthetic Pharmacology Basic Principles and Clinical Practice

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ISBN-10: 0521896665

ISBN-13: 9780521896665

Edition: 2nd 2011

Authors: Alex S. Evers, Mervyn Maze, Evan D. Kharasch

List price: $284.00
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Book details

List price: $284.00
Edition: 2nd
Copyright year: 2011
Publisher: Cambridge University Press
Publication date: 3/10/2011
Pages: 1262
Size: 8.86" wide x 11.14" long x 2.48" tall
Weight: 9.042
Language: English

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Professor Mervyn Maze is Chair, Department of Anesthesia and Perioperative Care, University of California, San Francisco, USA.

Evan Kharasch is Russell D. and Mary B. Shelden Professor of Anesthesiology, Director, Division of Clinical and Translational Research, Department of Anesthesiology, and Professor of Biochemistry and Molecular Biophysics, Washington University, USA.

Preface to the first edition
Preface to the second edition
Principles of Drug Action
Pharmacodynamic principles of drug action
G protein coupled receptors
Other signalling pathways
Signal transduction mechanisms: ion channels
Principles of pharmacokinetics
Principles of drug transformation
Drug transport and transporters
Target controlled infusions and closed loop administration
Alternate routes of drug administration
Principles of pharmacogenetics
Pharmacodynamic drug interactions in anesthetic practice
Pharmacoeconomics
Physiologic Substrates of Drug Action
Sleep and consciousness
Synaptic transmission
Memory, learning and cognition
Mechanisms of pain transmission and transduction
Generation and propagation of action potentials
Neuromuscular junction
Vascular reactivity
Cardiac rhythm
Myocardial performance
Autonomic function
Physiology of immunity and inflammation
Essential Drugs in Anesthetic Practice
Mechanisms of anesthetic action
Pharmacokinetics of inhaled anesthetics
Clinical pharmacology of inhaled anesthetics
Pharmacokinetics of intravenous anesthetics
Clinical pharmacology of intravenous anesthetics
Benzodiazepines
�-2 Agonists and other sedatives and amnestics
Mechanisms of action of opioids
Pharmacokinetics of opioids
Clinical pharmacology of opioids
Nonsteroidal anti-inflammatory drugs
Other ion channel and receptor ligands for analgesia
Local anesthetics
Anticonvulsant and antipsychotic drugs
Neuromuscular blocking agents
Reversal drugs
Sympathomimetics and vasoconstrictors
Parasympathomimetic and parasympatholytic drugs
�-blockers and other adrenergic receptor antagonists
Antiarrhythmic agents
Positive inotropic drugs
Vasodilators (incl. ACE inhibitors and NO)
Calcium channel blockers
Bronchodilators
Pulmonary vasodilators
Drugs acting via the kidney
Fluids and electrolytes as pharmacologic agents
Corticosteroids and anti-inflammatory agents
Anti-rejection drugs and immunosuppressants
Antimotility and antisecretory agents
Antiemetics
Insulin and anti-hyperglycemic agents
Nutritional elements of management
Agents affecting coagulation and platelet function
Obstetrical adjuvants and obstetric pharmacology
Antimicrobial therapy
Clinical Application and Anesthesia Practice (Evidence Based, Rational Drug Selection, Management)
Pre-operative management
Induction of anesthesia
Maintenance and emergence from anesthesia
Management of sedation, analgesia and delirium
Post-operative analgesia
Control of blood pressure and vascular tone
Cardiac protection and pharmacologic management of myocardial ischemia
Management of patients with chronic alcohol or drug use
Drug allergy and treatment
Special populations - pediatric
Special populations - geriatric
Emerging concepts: neuroprotection and neurotoxicity
Index