| |
| |
| Preface | |
| |
| |
| General References | |
| |
| |
| |
| The Disconnection Approach | |
| |
| |
| |
| Basic Principles: Synthons and Reagents Synthesis of Aromatic Compounds | |
| |
| |
| |
| Strategy I: The Order of Events | |
| |
| |
| |
| One-Group C-X Disconnections | |
| |
| |
| |
| Strategy II: Chemoselectivity | |
| |
| |
| |
| Two-Group C-X Disconnections | |
| |
| |
| |
| Strategy III: Reversal of Polarity, Cyclisations, Summary of Strategy | |
| |
| |
| |
| Amine Synthesis | |
| |
| |
| |
| Strategy IV: Protecting Groups | |
| |
| |
| |
| One Group C-C Disconnections I: Alcohols | |
| |
| |
| |
| General Strategy A: Choosing a Disconnection | |
| |
| |
| |
| Strategy V: Stereoselectivity A | |
| |
| |
| |
| One Group C-C Disconnections II: Carbonyl Compounds | |
| |
| |
| |
| Strategy VI: Regioselectivity | |
| |
| |
| |
| Alkene Synthesis | |
| |
| |
| |
| Strategy VII: Use of Acetylenes (Alkynes) | |
| |
| |
| |
| Two-Group C-C Disconnections I: Diels-Alder Reactions | |
| |
| |
| |
| Strategy VIII: Introduction to Carbonyl Condensations | |
| |
| |
| |
| Two-Group C-C Disconnections II: 1,3-Difunctionalised Compounds | |
| |
| |
| |
| Strategy IX: Control in Carbonyl Condensations | |
| |
| |
| |
| Two-Group C-C Disconnections III: 1,5-Difunctionalised Compounds Conjugate (Michael) Addition and Robinson Annelation | |
| |
| |
| |
| Strategy X: Aliphatic Nitro Compounds in Synthesis | |
| |
| |
| |
| Two-Group Disconnections IV: 1,2-Difunctionalised Compounds | |
| |
| |
| |
| Strategy XI: Radical Reactions in Synthesis | |
| |
| |
| |
| Two-Group Disconnections V: 1,4-Difunctionalised Compounds | |
| |
| |
| |
| Strategy XII: Reconnection | |
| |
| |
| |
| Two-Group C-C Disconnections VI: 1,6-diCarbonyl Compounds | |
| |
| |
| |
| General Strategy B: Strategy of Carbonyl Disconnections | |
| |
| |
| |
| Strategy XIII: Introduction to Ring Synthesis: Saturated Heterocycles | |
| |
| |
| |
| Three-Membered Rings | |
| |
| |
| |
| Strategy XIV: Rearrangements in Synthesis | |
| |
| |
| |
| Four-Membered Rings: Photochemistry in Synthesis | |
| |
| |
| |
| Strategy XV: The Use of Ketenes in Synthesis | |
| |
| |
| |
| Five-Membered Rings | |
| |
| |
| |
| Strategy XVI: Pericyclic Reactions in Synthesis: Special Methods for Five-Membered Rings | |
| |
| |
| |
| Six-Membered Rings | |
| |
| |
| |
| General Strategy C: Strategy of Ring Synthesis | |
| |
| |
| |
| Strategy XVII: Stereoselectivity B | |
| |
| |
| |
| Aromatic Heterocycles | |
| |
| |
| |
| General Strategy D: Advanced Strategy | |
| |
| |
| Index | |