Cellular Biophysics Electrical Properties

ISBN-10: 0262231840

ISBN-13: 9780262231848

Edition: 1996

Authors: Thomas F. Weiss
List price: $72.00
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Description: Cellular Biophysics is a quantitatively oriented basic physiology text for senior undergraduate and graduate students in bioengineering, biophysics, physiology, and neuroscience programs. It will also serve as a major reference work for biophysicists. Developed from the author's notes for a course that he has taught at MIT for many years, these books provide a clear and logical explanation of the foundations of cell biophysics, teaching transport and the electrical properties of cells from a combined biological, physical, and engineering viewpoint. Each volume contains introductory chapters that motivate the material and present it in a broad historical context. Important experimental results and methods are described. Theories are derived almost always from first principles so that students develop an understanding of not only the predictions of the theory but also its limitations. Theoretical results are compared carefully with experimental findings and new results appear throughout. There are many time-tested exercises and problems as well as extensive lists of references. The volume on the electrical properties of cells covers both electrically inexcitable cells as well as electrically excitable cells such as neurons and muscle cells. Included are chapters on lumped-parameter and distributed-parameter models of cells, linear electric properties of cells, the Hodgkin-Huxley model of the giant axon of the squid, saltatory conduction in myelinated nerve fibers, and voltage-gated ion channels.

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Book details

List price: $72.00
Copyright year: 1996
Publisher: MIT Press
Publication date: 3/6/1996
Binding: Hardcover
Pages: 590
Size: 8.50" wide x 9.50" long x 1.25" tall
Weight: 3.146
Language: English

Electrical Properties
Units, Physical Constants, List of Symbols
Electric Properties of Cells
A Brief Historical Perspective
Cellular Electric Potentials
Mechanisms of Generation of Membrane Potentials
Information Coding
The Marvelous Giant Axon of the Squid
Lumped- and Distributed-Parameter Models
Introduction
Electric Variables
Electrically Small Cells
Electrically Large Cells- The Core Conductor Model
Linear Electric Properties of Cells
Introduction
Membrane Electrical Properties
Electrically Small Cells
Electrically Large Cells- The Cable Model
Hodgkin-Huxley Model
Introduction
Ionic Mechanisms
Synthesis
Explanation of Electrical Excitability
Saltatory Conduction
Structure of Myelinated Fibers
Physiological Evidence
Electrical Properties of Myelinated Fibers
Model for Saltatory Conduction
Conduction Velocity of Myelinated Fibers
What Causes Saltatory Conduction?
Voltage-Gated Ion Channels
Historical Perspective
Macroscopic Ionic Currents
Gating Currents
Single-Channel Currents
Two-State Gate
Multiple-State Channels
Ion Channel Macromolecules
Index
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