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Quest for the Cure The Science and Stories Behind the Next Generation of Medicines

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ISBN-10: 0231152124

ISBN-13: 9780231152129

Edition: 2011

Authors: Brent Stockwell

List price: $28.00
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Description:

After more than fifty years of blockbuster drug development, skeptics are beginning to fear we may be reaching the end of drug discovery to combat major diseases. In this engaging book, Brent Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, the book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in World War led to early anti-cancer agents and how the efforts to decode the human genome might lead to new…    
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Book details

List price: $28.00
Copyright year: 2011
Publisher: Columbia University Press
Publication date: 5/17/2011
Binding: Hardcover
Pages: 284
Size: 0.56" wide x 0.85" long x 0.09" tall
Weight: 0.990
Language: English

List of Illustrations
Preface
Acknowledgments
Abbreviations
The Vanishing Cures
The Drug Discovery Crisis
A New Science of Molecules
The Birth of the First Cancer Drugs
A New Company Creating Drug Combinations
The Undruggable RAS Protein
The Druggable Genome
The Path to the Next Generation of Medicines
Peering Inside Proteins
The Nature of Interactions Between Proteins
From Protein-Protein Interactions to Personalized Medicines
A Revolution in Peptide Synthesis
A Vast Array of Drug Candidates
Moving Outside the Small Molecule Box
Acceleratingthe Arrival of Next-Generation Drugs
Notes
Glossary
Index