Introduction to Medicinal Chemistry

Name: Introduction to Medicinal Chemistry
Price: 8.44 USD
Availability: InStock
ISBN: 9780199234479

ISBN-10: 0199234477

ISBN-13: 9780199234479

Edition: 4th 2009

Authors: Graham L. Patrick

List price: $67.99

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Description:

The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is veryaccessible to students.Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitorsto painkillers.The book builds on the history of drug development, but does not assume much…

Book details

List price: $67.99
Edition: 4th
Copyright year: 2009
Publisher: Oxford University Press, Incorporated
Publication date: 3/25/2009
Binding: Paperback
Pages: 752
Size: 7.68" wide x 10.43" long x 0.07" tall
Weight: 3.498
Language: English




Drugs and drug targets: an overview



Drug targets: Structure and Function



Protein structure and function



Enzymes: structure and function



Receptors: structure and function



Receptors and signal transduction



Nucleic acids - structure and function



Pharmacodynamics and pharmacokinetics



Enzymes as drug targets



Receptors as drug targets



Nucleic acids as drug targets



Other drug targets



Pharmacokinetics and related topics



Statins



Drug discovery, design, and development



Drug discovery: finding a lead



Drug design: optimizing target interactions



Drug design: optimizing access to the target



Drug development



The design of ACE inhibitors



Artemisinin and related antimalarial drugs



The design of oxamniquine



Tools of the trade



Combinatorial synthesis



Computers in medicinal chemistry



Quantitative structure-activity relationships (QSAR)



De novo design of a thymidylate synthase inhibitor



Design of a serotonin antagonist



Selected topics in medicinal chemistry



Antibacterial agents



Antiviral agents



Anticancer agents



The peripheral nervous system: cholinergics, anticholinergics, and anticholinesterases



The andrenergic nervous system



The opium analgesics



Anti-ulcer agents