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Essentials of Stem Cell Biology

ISBN-10: 0123747295
ISBN-13: 9780123747297
Edition: 2nd 2009
List price: $240.00
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Description: First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest  More...

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Book details

List price: $240.00
Edition: 2nd
Copyright year: 2009
Publisher: Elsevier Science & Technology Books
Publication date: 6/22/2009
Binding: Hardcover
Pages: 680
Size: 9.00" wide x 11.25" long x 1.50" tall
Weight: 5.192
Language: English

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world?s experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. * Contributions by Nobel Laureates and leading international investigators * Includes two entirely new chapters devoted exclusively to iPS written by the scientists who made the breakthroug * Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate

Foreword
Why Stem Cell Research?
A New Path ?
Induced Pluripotent Stem Cells
Embryonic Stem Cells
Versus Adult Stem Cells
'Stemness': Definitions, Criteria and Standards
Introduction to Stem Cells
Present Perspective and Future Challenges
Embryonic Stem Cells in Perspective
The Development of Epithelial Stem Cell Concepts
The Advent of Direct Reprogramming
Clinical Translation of Stem Cells
Basic Biology Mechanisms
Molecular Basis of Pluripotency
Stem Cell Niches
Mechanisms of Stem Cell Self-Renewal
Cell Cycle Regulators in Stem Cells
Epigenetic Mechanisms of Cellular Memory
Cell Fusion and the Differentiated State
How Cells Change Their Phenotype
Tissue and Organ Development
Differentiation in Early Development
Primordial Germ Cells in Mouse and Human
Stem Cells in Extraembryonic Lineages
Amniotic Fluid Derived Pluripotent Cells
Cord Blood Stem Cells
Neurogenesis in the Vertebrate Embryo
The Nervous System
Neuronal Progenitors in the Adult Brain
Sensory Epithelium of the Eye and Ear
Epithelial Skin Stem Cells
The Ontogeny of the Hematopoietic System
Hematopoietic Stem Cells
Red Blood Cells
Cell Differentiation in the Skeleton
Vascular Progenitor Cells
Multipotent Adult Progenitor Cells
Mesenchymal Stem Cells
Skeletal Muscle Stem Cells
Stem Cells and the Regenerating Heart
Potential of ES Cell Differentiation Culture for Vascular Biology
Cell Lineages and Stem Cells in the Kidney
Adult Liver Stem Cells
Pancreatic Stem Cells
Stem Cells in the Gastrointestinal Tract
Stem Cells in the Lung
Methods
Generation of Induced Pluripotent Stem Cells
Characteristics and Characterization of Pluripotent Stem Cells
Isolation and Maintenance of Murine Embryonic Stem Cells
Isolation, Characterization, and Maintenance of Primate ES Cells
Approaches for Derivation and Maintenance of Human ES cells: Detailed Procedures and Alternatives
Derivation and Differentiation of Human EG Cells
Growth Factors & the Serum-Free Culture of Human Pluripotent Stem Cells
Feeder-Free Culture
Genetic Manipulation of Human Embryonic Stem Cells
Homologous Recombination in Human Embryonic Stem Cells
Surface Antigen Markers
Lineage Marking
Genomic Reprogramming
Isolation and Characterization of Hematopoietic Stem Cells
Microarray Analysis of Stem Cells and Differentiation
Zebrafish and Stem Cell Research
Applications
Cancer Stem Cells
Neural Stem Cells: Therapeutic Applications in Neurodegenerative Diseases
Spinal Cord Injury
Use of Embryonic Stem Cells to Treat Heart Disease
Insulin-Producing Cells Derived from Stem Cells: A Potential Treatment for Diabetes
Burns and Skin Ulcers 978-0-12-370465-8
Stem Cells and Heart Disease
Stem Cells for the Treatment of Muscular Dystropy
Skin Regeneration
Orthopaedic Applications of Stem Cells
Embryonic Stem Cells in Tissue Engineering
Adult Stem Cells in Tissue Engineering
Stem Cell Gene Therapy
Regulation and Ethics
Ethical Considerations
Religious Considerations
Regulatory Considerations
It�s Not About Curiosity, It�s About Cures
Epilogue: Concluding Statement

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